To acquire a deeper understanding of electrochemical systems requires techniques that
address nanoscale aspects of electrochemistry, inter alia, the detection and analysis of …

The ability to detect low concentrations of biomarkers in patient samples is one of the
cornerstones of modern healthcare. In general, biosensing approaches are based on …

Single-molecule tools enable translating biorecognition events into electrical and optical
signals at the single-molecule level. However, the limitations such as poor specificity, low …

Nanopore analysis of nucleic acid is now routine, but detection of proteins remains
challenging. Here, we report the systematic characterization of the effect of macromolecular …

DNA nanotechnology has paved the way for new generations of programmable
nanomaterials. Utilizing the DNA origami technique, various DNA constructs can be …

The translocation of double-stranded DNA through a solid-state nanopore may either
decrease or increase the ionic current depending on the ionic concentration of the …

Recent advances have proven that using solid-state nanopores is a promising single
molecular technique to enrich the DNA assembly signaling library. Other than using them for …

Controlled manipulation of cultured cells by delivery of exogenous macromolecules is a
cornerstone of experimental biology. Here we describe a platform that uses nanopipettes to …

DNA has been actively utilized as bricks to construct exquisite nanostructures due to their
unparalleled programmability. Particularly, nanostructures based on framework DNA (F …

With the development in DNA self-assembly technology, DNA origami nanostructures have
been widely applied in biomedical research. Solid-state nanopores represent an emerging …