Cannabis has been used for medicinal purposes for thousands of years. The prohibition of
cannabis in the middle of the 20th century has arrested cannabis research. In recent years …

In 1964, the psychoactive ingredient of Cannabis sativa, Δ 9-tetrahydrocannabinol (THC),
was isolated. Nearly 30 years later the endogenous counterparts of THC, collectively termed …

Oxidative stress contributes to the pathogenesis of acute lung injury. Protein S-
glutathionylation plays an important role in cellular antioxidant defense. Here we report that …

Some cannabinoids activate the different isoforms of PPARs (α, β and γ), as shown through
the use of reporter gene assays, binding studies, selective antagonists and knockout …

A great need exists for the development of new medications to treat pain resulting from
various disease states and types of injury. Given that the endogenous cannabinoid (that is …

The endocannabinoid system (ECS) has lately been proven to be an important, multifaceted
homeostatic regulator, which influences a wide-variety of physiological processes all over …

Chronic pain states are highly prevalent and yet poorly controlled by currently available
analgesics, representing an enormous clinical, societal, and economic burden. Existing pain …

Δ 9-Tetrahydrocannabinol (THC) and cannabidiol (CBD) occur naturally in marijuana
(Cannabis) and may be formulated, individually or in combination in pharmaceuticals such …

Over four decades have passed since liver fatty acid binding protein (FABP) 1 was first
isolated. There are few protein families for which most of the complete tertiary structures …

Metabolic reprogramming has been described in rapidly growing tumors, which are thought
to mostly contain fast‐cycling cells (FCC s) that have impaired mitochondrial function and …