Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic
acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor …

Midkine is a heparin-binding cytokine or a growth factor with a molecular weight of 13 kDa.
Midkine binds to oversulfated structures in heparan sulfate and chondroitin sulfate. The …

Midkine (MK) is a pleiotropic growth factor prominently expressed during embryogenesis but
down‐regulated to neglible levels in healthy adults. Many published studies have …

In recent years, it has become clear that the current standard therapeutic options for
pancreatic cancer are not adequate and still do not meet the criteria to cure patients …

Midkine (MK) is a heparin-binding cytokine, and promotes growth, survival, migration and
other activities of target cells. After describing the general properties of MK, this review …

Midkine (MK) is a growth/differentiation factor frequently expressed at high levels in some
types of human malignancies. To investigate whether MK is a useful marker in prostate …

Midkine (Mdk) is a multifunctional protein involved in inflammatory processes. Hence,
circulating Mdk is increased in sepsis and has been previously suggested as a potential …

Midkine (MDK) expression is associated with the proliferation of many cancers, including
glioma. However, the upstream signaling that leads to MDK accumulation remains elusive …

We have postulated that the lifetime protective effect of an early pregnancy against breast
cancer is due to the complete differentiation of the mammary gland characterized by a …

Midkine, a heparin‐binding growth factor, is up‐regulated in many types of cancer. The aim
of this study was to measure plasma midkine levels in patients with breast cancer and to …