[HTML][HTML] Society for Vascular Surgery practice guidelines for atherosclerotic occlusive disease of the lower extremities: management of asymptomatic disease and …

MS Conte, FB Pomposelli, DG Clair, PJ Geraghty… - Journal of vascular …, 2015 - Elsevier
Peripheral arterial disease (PAD) continues to grow in global prevalence and consumes an
increasing amount of resources in the United States health care system. Overall rates of …

Peripheral artery disease: evolving role of exercise, medical therapy, and endovascular options

JW Olin, CJ White, EJ Armstrong… - Journal of the American …, 2016 - jacc.org
The prevalence of peripheral artery disease (PAD) continues to increase worldwide. It is
important to identify patients with PAD because of the increased risk of myocardial infarction …

A review of the pathophysiology and potential biomarkers for peripheral artery disease

SM Krishna, JV Moxon, J Golledge - International journal of molecular …, 2015 - mdpi.com
Peripheral artery disease (PAD) is due to the blockage of the arteries supplying blood to the
lower limbs usually secondary to atherosclerosis. The most severe clinical manifestation of …

Pro-resolving lipid mediators in vascular disease

MS Conte, TA Desai, B Wu, M Schaller… - The Journal of clinical …, 2018 - Am Soc Clin Investig
Unresolved inflammation is central to the pathophysiology of commonly occurring vascular
diseases such as atherosclerosis, aneurysm, and deep vein thrombosis—conditions that are …

Oxidative stress in peripheral arterial disease (PAD) mechanism and biomarkers

SS Signorelli, S Scuto, E Marino, A Xourafa, A Gaudio - Antioxidants, 2019 - mdpi.com
Hemodynamic dysfunction mainly characterizes pathophysiology of peripheral arterial
disease (PAD) leading to chronic ischemia. Hemodynamic dysfunction is the origin of …

Validating fatty acid binding protein 3 as a diagnostic and prognostic biomarker for peripheral arterial disease: A three-year prospective follow-up study

A Zamzam, MH Syed, OD Rotstein, J Eikelboom… - …, 2023 - thelancet.com
Background Patients with peripheral arterial disease (PAD) often remain undiagnosed and
therefore suboptimally managed. Here, we investigated the diagnostic and prognostic …

Biochemical indices of oxidative stress and inflammation in the evaluation of peripheral artery disease

I Fort-Gallifa, A García-Heredia… - Free Radical Biology …, 2016 - Elsevier
Background The aims of this study were:(1) to investigate changes in indices of oxidative
stress and inflammation in the evaluation of peripheral artery disease (PAD);(2) to compare …

Microfibrillar-associated protein 4 variation in symptomatic peripheral artery disease

LE Hemstra, A Schlosser, JS Lindholt… - Journal of Translational …, 2018 - Springer
Background Symptomatic peripheral artery disease (PAD) is an atherosclerotic occlusive
disease affecting the lower extremities. The cause of symptomatic PAD is atherosclerosis …

Revisiting the middle molecule hypothesis of uremic toxicity: a systematic review of beta 2 microglobulin population kinetics and large scale modeling of hemodialysis …

ME Roumelioti, T Nolin, ML Unruh, C Argyropoulos - PLoS One, 2016 - journals.plos.org
Background Beta-2 Microglobulin (β2M) is a prototypical “middle molecule” uremic toxin that
has been associated with a higher risk of death in hemodialysis patients. A quantitative …

Association of peripheral arterial disease with all-cause and cardiovascular mortality in hemodialysis patients: a meta-analysis

Y Yang, Y Ning, W Shang, R Luo, L Li, S Guo, G Xu… - BMC nephrology, 2016 - Springer
Background Recent studies have shown an association between peripheral arterial disease
(PAD) and increased risk of mortality in hemodialysis (HD) patients; however, the estimates …