Directing coupled motion with light: a key step toward machine-like function

R Costil, M Holzheimer, S Crespi, NA Simeth… - Chemical …, 2021 - ACS Publications
Molecular photoactuators can control shape and chemical or physical properties of the
responsive system they are embedded in. These effects are usually mediated by …

[HTML][HTML] Integrating stimuli-responsive properties in host-guest supramolecular drug delivery systems

AS Braegelman, MJ Webber - Theranostics, 2019 - ncbi.nlm.nih.gov
Host-guest motifs are likely the most recognizable manifestation of supramolecular
chemistry. These complexes are characterized by the organization of small molecules on the …

A [2] rotaxane-based circularly polarized luminescence switch

AHG David, R Casares, JM Cuerva… - Journal of the …, 2019 - ACS Publications
A rotaxane-based molecular shuttle has been synthesized in which the switching of the
position of a fluorescent macrocycle on the thread turns “on” or “off” the circularly polarized …

Mechanically interlocked molecules in metal–organic frameworks

A Saura-Sanmartin, A Pastor… - Chemical Society …, 2022 - pubs.rsc.org
Mechanically interlocked molecules (MIMs) have great potential in the development of
molecular machinery due to their intercomponent dynamics. The incorporation of these …

Copper-linked rotaxanes for the building of photoresponsive metal organic frameworks with controlled cargo delivery

A Saura-Sanmartin, A Martinez-Cuezva… - Journal of the …, 2020 - ACS Publications
We have prepared a photoresponsive metal–organic framework by using an amide-based
[2] rotaxane as linker and copper (II) ions as metal nodes. The interlocked linker was …

Pyridyl-acyl hydrazone rotaxanes and molecular shuttles

DA Leigh, V Marcos, T Nalbantoglu… - Journal of the …, 2017 - ACS Publications
We report on rotaxanes featuring a pyridyl-acyl hydrazone moiety on the axle as a
photo/thermal-switchable macrocycle binding site. The pyridyl-acyl E-hydrazone acts as a …

Photoswitchable interlocked thiodiglycolamide as a cocatalyst of a chalcogeno-Baylis–Hillman reaction

A Martinez-Cuezva, A Saura-Sanmartin… - Chemical …, 2017 - pubs.rsc.org
En route to a photoswitchable interlocked catalyst we have proved the ability of
thiodiglycolamide to act as a template in the formation of hydrogen-bonded [2] rotaxanes. X …

Stereocontrolled synthesis of β-lactams within [2] rotaxanes: showcasing the chemical consequences of the mechanical bond

A Martinez-Cuezva, C Lopez-Leonardo… - Journal of the …, 2016 - ACS Publications
The intramolecular cyclization of N-benzylfumaramide [2] rotaxanes is described. The
mechanical bond of these substrates activates this transformation to proceed in high yields …

pH and redox dual-responsive MSN-SS-CS as a drug delivery system in cancer therapy

Y Xu, L Xiao, Y Chang, Y Cao, C Chen, D Wang - Materials, 2020 - mdpi.com
In order to achieve a controlled release drug delivery system (DDS) for cancer therapy, a pH
and redox dual-responsive mesoporous silica nanoparticles (MSN)-sulfur (S)-S-chitosan …

ROS-responsive mesoporous silica nanoparticles for MR imaging-guided photodynamically maneuvered chemotherapy

V Rao, HS Han, H Lee, S Jeon, DW Jung, J Lee, GR Yi… - Nanoscale, 2018 - pubs.rsc.org
Mesoporous silica nanoparticles (MSNs) with stimuli-responsive gatekeepers have been
extensively investigated for controlled drug delivery at the target sites. Herein, we developed …