The changing landscape of atherosclerosis

P Libby - Nature, 2021 - nature.com
Emerging evidence has spurred a considerable evolution of concepts relating to
atherosclerosis, and has called into question many previous notions. Here I review this …

Inflamm-ageing: the role of inflammation in age-dependent cardiovascular disease

L Liberale, F Montecucco, JC Tardif… - European heart …, 2020 - academic.oup.com
The ongoing worldwide increase in life expectancy portends a rising prevalence of age-
related cardiovascular (CV) diseases in the coming decades that demands a deeper …

2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic …

AR Lyon, T Lopez-Fernandez, LS Couch… - European Heart …, 2022 - academic.oup.com
ESC Guidelines e341 (1) the specific situation of the patient. In this respect, it is specified
that, unless otherwise provided for by national regulations, offlabel use of medication should …

TET2-driven clonal hematopoiesis and response to canakinumab: an exploratory analysis of the CANTOS randomized clinical trial

EC Svensson, A Madar, CD Campbell, Y He… - JAMA …, 2022 - jamanetwork.com
Importance Clonal hematopoiesis of indeterminate potential (CHIP) is associated with
increased risk of atherosclerotic cardiovascular disease, and mouse experiments suggest …

Association of clonal hematopoiesis with incident heart failure

B Yu, MB Roberts, LM Raffield, SM Zekavat… - Journal of the American …, 2021 - jacc.org
Background Age-related clonal hematopoiesis of indeterminate potential (CHIP), defined as
clonally expanded leukemogenic sequence variations (particularly in DNMT3A, TET2 …

Implantable triboelectric nanogenerators for self‐powered cardiovascular healthcare

Z Che, S O'Donovan, X Xiao, X Wan, G Chen, X Zhao… - Small, 2023 - Wiley Online Library
Triboelectric nanogenerators (TENGs) have gained significant traction in recent years in the
bioengineering community. With the potential for expansive applications for biomedical use …

Clonal hematopoiesis and risk of progression of heart failure with reduced left ventricular ejection fraction

DA Pascual-Figal, A Bayes-Genis, M Díez-Díez… - Journal of the American …, 2021 - jacc.org
Background Clonal hematopoiesis driven by somatic mutations in hematopoietic cells,
frequently called clonal hematopoiesis of indeterminate potential (CHIP), has been …

Clonal hematopoiesis: Mutation-specific adaptation to environmental change

MA Florez, BT Tran, TK Wathan, J DeGregori… - Cell Stem Cell, 2022 - cell.com
Clonal hematopoiesis of indeterminate potential (CHIP) describes a widespread expansion
of genetically variant hematopoietic cells that increases exponentially with age and is …

Cardio-onco-metabolism: metabolic remodelling in cardiovascular disease and cancer

A Karlstaedt, J Moslehi, RA de Boer - Nature Reviews Cardiology, 2022 - nature.com
Cardiovascular disease and cancer are the two leading causes of morbidity and mortality in
the world. The emerging field of cardio-oncology has revealed that these seemingly …

Clonal hematopoiesis of indeterminate potential predicts adverse outcomes in patients with atherosclerotic cardiovascular disease

ED Gumuser, A Schuermans, SMJ Cho… - Journal of the American …, 2023 - jacc.org
Background Clonal hematopoiesis of indeterminate potential (CHIP)—the age-related clonal
expansion of blood stem cells with leukemia-associated mutations—is a novel …