Exploring advanced materials: Harnessing the synergy of inverse gas chromatography and artificial vision intelligence

PK Basivi, T Hamieh, V Kakani, VR Pasupuleti… - TrAC Trends in …, 2024 - Elsevier
Inverse gas chromatography (IGC) has emerged as a highly sensitive, adaptable, and
effective technology for material analysis. Through employing thermochemical approaches …

High dose dry powder inhalers to overcome the challenges of tuberculosis treatment

MAM Momin, IG Tucker, SC Das - International journal of pharmaceutics, 2018 - Elsevier
Tuberculosis (TB) is a major global health burden. The emergence of the human
immunodeficiency virus (HIV) epidemic and drug resistance has complicated global TB …

In Vitro Testing for Orally Inhaled Products: Developments in Science-Based Regulatory Approaches

B Forbes, P Bäckman, D Christopher, M Dolovich… - The AAPS journal, 2015 - Springer
This article is part of a series of reports from the “Orlando Inhalation Conference-Approaches
in International Regulation” which was held in March 2014, and coorganized by the …

Inhaled dry powder formulations for treating tuberculosis

S Das, I Tucker, P Stewart - Current Drug Delivery, 2015 - ingentaconnect.com
Tuberculosis is the second leading cause of death from infectious diseases. Although
antitubercular drugs have been traditionally administered orally, there is a growing interest …

[HTML][HTML] Rapid characterisation of the inherent dispersibility of respirable powders using dry dispersion laser diffraction

S Jaffari, B Forbes, E Collins, DJ Barlow… - International journal of …, 2013 - Elsevier
Understanding and controlling powder de-agglomeration is of great importance in the
development of dry powder inhaler (DPI) products. Dry dispersion laser diffraction measures …

Co-spray drying of hygroscopic kanamycin with the hydrophobic drug rifampicin to improve the aerosolization of kanamycin powder for treating respiratory infections

MAM Momin, IG Tucker, CS Doyle, JA Denman… - International journal of …, 2018 - Elsevier
High dose delivery of drugs to the lung using a dry powder inhaler (DPI) is an emerging
approach to combat drug-resistant local infections. To achieve this, highly aerosolizable …

Formulation pre-screening of inhalation powders using computational atom–atom systematic search method

V Ramachandran, D Murnane… - Molecular …, 2015 - ACS Publications
The synthonic modeling approach provides a molecule-centered understanding of the
surface properties of crystals. It has been applied extensively to understand crystallization …

Manipulation of spray-drying conditions to develop dry powder particles with surfaces enriched in hydrophobic material to achieve high aerosolization of a …

MAM Momin, IG Tucker, CS Doyle, JA Denman… - International journal of …, 2018 - Elsevier
This study aimed to develop dry powder particles with surfaces enriched in hydrophobic
material by manipulation of spray-drying conditions and to investigate the effect of …

Pulmonary targeting potential of rosuvastatin loaded nanostructured lipid carrier: Optimization by factorial design

A Patil-Gadhe, V Pokharkar - International Journal of Pharmaceutics, 2016 - Elsevier
Abstract Rosuvastatin (RSVS), an anti-lipidemic agent suggested for the treatment of airway
remodeling in chronic obstructive pulmonary disease (COPD). It shows a pleiotropic effect …

Automated Filling Equipment Allows Increase in the Maximum Dose to Be Filled in the Cyclops® High Dose Dry Powder Inhalation Device While Maintaining …

I Sibum, P Hagedoorn, CO Botterman, HW Frijlink… - Pharmaceutics, 2020 - mdpi.com
In recent years there has been increasing interest in the pulmonary delivery of high dose dry
powder drugs, such as antibiotics. Drugs in this class need to be dosed in doses far over 2.5 …