Pulmonary arterial hypertension

PM Hassoun - New England Journal of Medicine, 2021 - Mass Medical Soc
Pulmonary Arterial Hypertension Without effective treatment, pulmonary arterial
hypertension results in high morbidity and mortality. This review discusses the pathogenesis …

Risk stratification and treatment goals in pulmonary arterial hypertension

F Dardi, A Boucly, R Benza, R Frantz… - European …, 2024 - publications.ersnet.org
Risk stratification has gained an increasing role in predicting outcomes and guiding the
treatment of patients with pulmonary arterial hypertension (PAH). The most predictive …

[HTML][HTML] Development and validation of an abridged version of the REVEAL 2.0 risk score calculator, REVEAL Lite 2, for use in patients with pulmonary arterial …

RL Benza, MK Kanwar, A Raina, JV Scott, CL Zhao… - Chest, 2021 - Elsevier
Background Achievement of low-risk status is a treatment goal in pulmonary arterial
hypertension (PAH). Risk assessment often is performed using multiparameter tools, such …

Artificial intelligence technologies in cardiology

Ł Ledziński, G Grześk - Journal of Cardiovascular Development and …, 2023 - mdpi.com
As the world produces exabytes of data, there is a growing need to find new methods that
are more suitable for dealing with complex datasets. Artificial intelligence (AI) has significant …

Harnessing big data to advance treatment and understanding of pulmonary hypertension

CJ Rhodes, AJ Sweatt, BA Maron - Circulation research, 2022 - Am Heart Assoc
Pulmonary hypertension is a complex disease with multiple causes, corresponding to
phenotypic heterogeneity and variable therapeutic responses. Advancing understanding of …

[HTML][HTML] A machine learning approach for mortality prediction in COVID-19 pneumonia: development and evaluation of the Piacenza score

G Halasz, M Sperti, M Villani, U Michelucci… - Journal of Medical …, 2021 - jmir.org
Background Several models have been developed to predict mortality in patients with
COVID-19 pneumonia, but only a few have demonstrated enough discriminatory capacity …

Pathophysiology of the right ventricle and its pulmonary vascular interaction

AR Hemnes, DS Celermajer, M D'Alto… - European …, 2024 - publications.ersnet.org
The right ventricle and its stress response is perhaps the most important arbiter of survival in
patients with pulmonary hypertension of many causes. The physiology of the …

Elevated pulmonary arterial compliance is associated with survival in pulmonary hypertension: results from a novel network medicine analysis

RS Wang, S Huang, SW Waldo, E Hess… - American Journal of …, 2023 - atsjournals.org
Rationale: Predictors of adverse outcome in pulmonary hypertension (PH) are well
established; however, data that inform survival are lacking. Objectives: We aim to identify …

[HTML][HTML] Comparing Explainable Machine Learning Approaches With Traditional Statistical Methods for Evaluating Stroke Risk Models: Retrospective Cohort Study

S Lolak, J Attia, GJ McKay, A Thakkinstian - JMIR cardio, 2023 - cardio.jmir.org
Background Stroke has multiple modifiable and nonmodifiable risk factors and represents a
leading cause of death globally. Understanding the complex interplay of stroke risk factors is …

[HTML][HTML] The right heart network and risk stratification in pulmonary arterial hypertension

F Haddad, K Contrepois, M Amsallem, AY Denault… - Chest, 2022 - Elsevier
Background Prognosis in pulmonary arterial hypertension (PAH) is closely related to
indexes of right ventricular function. A better understanding of their relationship may provide …