Multi-scale modelling and simulation in systems biology

JO Dada, P Mendes - Integrative Biology, 2011 - academic.oup.com
The aim of systems biology is to describe and understand biology at a global scale where
biological functions are recognised as a result of complex mechanisms that happen at …

Regenerative medicine meets mathematical modelling: developing symbiotic relationships

SL Waters, LJ Schumacher, AJ El Haj - npj Regenerative Medicine, 2021 - nature.com
Successful progression from bench to bedside for regenerative medicine products is
challenging and requires a multidisciplinary approach. What has not yet been fully …

A thermodynamic switch modulates abscisic acid receptor sensitivity

F Dupeux, J Santiago, K Betz, J Twycross… - The EMBO …, 2011 - embopress.org
Abscisic acid (ABA) is a key hormone regulating plant growth, development and the
response to biotic and abiotic stress. ABA binding to pyrabactin resistance (PYR)/PYR1‐like …

Spatial stochastic intracellular kinetics: A review of modelling approaches

S Smith, R Grima - Bulletin of mathematical biology, 2019 - Springer
Abstract Models of chemical kinetics that incorporate both stochasticity and diffusion are an
increasingly common tool for studying biology. The variety of competing models is vast, but …

Single-cell variability in multicellular organisms

S Smith, R Grima - Nature communications, 2018 - nature.com
Noisy gene expression is of fundamental importance to single cells, and is therefore widely
studied in single-celled organisms. Extending these studies to multicellular organisms is …

Plant systems biology: network matters

M Lucas, L Laplaze, MJ Bennett - Plant, cell & environment, 2011 - Wiley Online Library
Systems biology is all about networks. A recent trend has been to associate systems biology
exclusively with the study of gene regulatory or protein‐interaction networks. However …

Multiscale systems analysis of root growth and development: modeling beyond the network and cellular scales

LR Band, JA Fozard, C Godin, OE Jensen… - The Plant …, 2012 - academic.oup.com
Over recent decades, we have gained detailed knowledge of many processes involved in
root growth and development. However, with this knowledge come increasing complexity …

The ten grand challenges of synthetic life

M Porcar, A Danchin, V de Lorenzo… - Systems and synthetic …, 2011 - Springer
The construction of artificial life is one of the main scientific challenges of the Synthetic
Biology era. Advances in DNA synthesis and a better understanding of regulatory processes …

Auxin Carriers Localization Drives Auxin Accumulation in Plant Cells Infected by Frankia in Casuarina glauca Actinorhizal Nodules

F Perrine-Walker, P Doumas, M Lucas… - Plant …, 2010 - academic.oup.com
Actinorhizal symbioses are mutualistic interactions between plants and the soil bacteria
Frankia that lead to the formation of nitrogen-fixing root nodules. Little is known about the …

[PDF][PDF] Identification method of attack path based on immune intrusion detection

H Wenhua, Y Geng - Journal of Networks, 2014 - Citeseer
This thesis takes researches on the immune intrusion detection and IP trace back
technology. To find out the network data features of the real-time analyses, the distributed …