Next-generation data filtering in the genomics era

W Hemstrom, JA Grummer, G Luikart… - Nature Reviews …, 2024 - nature.com
Genomic data are ubiquitous across disciplines, from agriculture to biodiversity, ecology,
evolution and human health. However, these datasets often contain noise or errors and are …

Performance of gut Microbiome as an independent diagnostic tool for 20 diseases: cross-cohort validation of machine-learning classifiers

M Li, J Liu, J Zhu, H Wang, C Sun, NL Gao… - Gut …, 2023 - Taylor & Francis
Cross-cohort validation is essential for gut-microbiome-based disease stratification but was
only performed for limited diseases. Here, we systematically evaluated the cross-cohort …

[HTML][HTML] A realistic benchmark for differential abundance testing and confounder adjustment in human microbiome studies

J Wirbel, M Essex, SK Forslund, G Zeller - Genome Biology, 2024 - Springer
Background In microbiome disease association studies, it is a fundamental task to test which
microbes differ in their abundance between groups. Yet, consensus on suitable or optimal …

[HTML][HTML] The Beneficial Effects of Lacticaseibacillus paracasei subsp. paracasei DSM 27449 in a Letrozole-Induced Polycystic Ovary Syndrome Rat Model

YZ Lee, SH Cheng, YF Lin, CC Wu, YC Tsai - International Journal of …, 2024 - mdpi.com
Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder affecting women of
reproductive age globally. Emerging evidence suggests that the dysregulation of microRNAs …

Environmental bacteria increase population growth of hydra at low temperature

M Miklós, K Cseri, L Laczkó, G Kardos… - Frontiers in …, 2023 - frontiersin.org
Multicellular organisms engage in complex ecological interactions with microorganisms,
some of which are harmful to the host's health and fitness (eg, pathogens or toxin-producing …

Predicting Personalized Diets Based on Microbial Characteristics between Patients with Superficial Gastritis and Atrophic Gastritis

X Gao, P Yin, Y Ren, L Yu, F Tian, J Zhao, W Chen… - Nutrients, 2023 - mdpi.com
Background: gastritis is a common stomach disease with a high global incidence and can
potentially develop into gastric cancer. The treatment of gastritis focuses on medication or …

GEMimp: An Accurate and Robust Imputation Method for Microbiome Data Using Graph Embedding Neural Network

Z Sun, K Song - Journal of Molecular Biology, 2024 - Elsevier
Microbiome research has increasingly underscored the profound link between microbial
compositions and human health, with numerous studies establishing a strong correlation …

A realistic benchmark for the identification of differentially abundant taxa in (confounded) human microbiome studies

J Wirbel, M Essex, SK Forslund, G Zeller - bioRxiv, 2022 - biorxiv.org
Background In microbiome disease association studies, it is a fundamental task to test which
microbes differ in their abundance between groups. Yet, consensus on suitable or optimal …

gLinDA: global differential abundance analysis of microbiomes

L Fehse, M Tajabadi, R Martin, H Holzmann, D Heider - bioRxiv, 2024 - biorxiv.org
Microbiome composition plays a significant role in various diseases, including cancer,
obesity, inflammatory bowel disease, and mental health disorders. Understanding the …

Utilizing the biosimulator to analyze the environmental microbiome within the intensive care units of a hospital

S Thomas, K Bittinger, LL Livornese Jr - 2024 - researchsquare.com
In our previous study, we demonstrated the ability of an engraved Petri dish, referred to as a"
biosimulator," to induce adhesion of non-adherent cells and the microbiome. This paper …