Regulation of Staphylococcus aureus Virulence

C Jenul, AR Horswill - Microbiology spectrum, 2019 - Am Soc Microbiol
Staphylococcus aureus is a Gram-positive opportunistic pathogen that has evolved a
complex regulatory network to control virulence. One of the main functions of this …

[HTML][HTML] Biofilms by bacterial human pathogens: Clinical relevance-development, composition and regulation-therapeutical strategies

A Schulze, F Mitterer, JP Pombo, S Schild - Microbial Cell, 2021 - ncbi.nlm.nih.gov
Notably, bacterial biofilm formation is increasingly recognized as a passive virulence factor
facilitating many infectious disease processes. In this review we will focus on bacterial …

[HTML][HTML] Natural transformation allows transfer of SCCmec-mediated methicillin resistance in Staphylococcus aureus biofilms

M Maree, LT Thi Nguyen, RL Ohniwa… - Nature …, 2022 - nature.com
SCC mec is a large mobile genetic element that includes the mecA gene and confers
resistance to β-lactam antibiotics in methicillin-resistant Staphylococcus aureus (MRSA) …

A catalogue of signal molecules that interact with sensor kinases, chemoreceptors and transcriptional regulators

MA Matilla, F Velando, D Martín-Mora… - FEMS Microbiology …, 2022 - academic.oup.com
Bacteria have evolved many different signal transduction systems that sense signals and
generate a variety of responses. Generally, most abundant are transcriptional regulators …

[HTML][HTML] Two-component systems of S. aureus: signaling and sensing mechanisms

L Bleul, P Francois, C Wolz - Genes, 2022 - mdpi.com
Genes | Free Full-Text | Two-Component Systems of S. aureus: Signaling and Sensing Mechanisms
Next Article in Journal Genome-Wide Identification, Primary Functional Characterization of the …

[HTML][HTML] Bacterial Targets of Antibiotics in Methicillin-Resistant Staphylococcus aureus

H Lade, JS Kim - Antibiotics, 2021 - mdpi.com
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most prevalent bacterial
pathogens and continues to be a leading cause of morbidity and mortality worldwide. MRSA …

[HTML][HTML] Intracellular Habitation of Staphylococcus aureus: Molecular Mechanisms and Prospects for Antimicrobial Therapy

JW Hommes, BGJ Surewaard - Biomedicines, 2022 - mdpi.com
Methicillin-resistant Staphylococcus aureus (MRSA) infections pose a global health threat,
especially with the continuous development of antibiotic resistance. As an opportunistic …

[HTML][HTML] The influenza-injured lung microenvironment promotes MRSA virulence, contributing to severe secondary bacterial pneumonia

C Langouët-Astrié, K Oshima, SA McMurtry, Y Yang… - Cell reports, 2022 - cell.com
Influenza infection is substantially worsened by the onset of secondary pneumonia caused
by bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA). The bidirectional …

The Staphylococcus aureus ArlRS two‐component system regulates virulence factor expression through MgrA

HA Crosby, N Tiwari, JM Kwiecinski, Z Xu… - Molecular …, 2020 - Wiley Online Library
Summary The Gram‐positive bacterium, Staphylococcus aureus, is a versatile pathogen that
can sense and adapt to a wide variety of environments within the human host, in part …

Structural Element of Vitamin U‐Mimicking Antibacterial Polypeptide with Ultrahigh Selectivity for Effectively Treating MRSA Infections

Z Zhang, X Wang, J Liu, H Yang, H Tang… - Angewandte Chemie …, 2024 - Wiley Online Library
Antimicrobial peptides (AMPs) exhibit mighty antibacterial properties without inducing drug
resistance. Achieving much higher selectivity of AMPs towards bacteria and normal cells has …