Reactive oxygen species: Physiological and physiopathological effects on synaptic plasticity: Supplementary issue: Brain plasticity and repair
TF Beckhauser, J Francis-Oliveira… - Journal of …, 2016 - journals.sagepub.com
In the mammalian central nervous system, reactive oxygen species (ROS) generation is
counterbalanced by antioxidant defenses. When large amounts of ROS accumulate …
counterbalanced by antioxidant defenses. When large amounts of ROS accumulate …
Nitric oxide function in plant biology: a redox cue in deconvolution
Nitric oxide (NO), a gaseous, redox‐active small molecule, is gradually becoming
established as a central regulator of growth, development, immunity and environmental …
established as a central regulator of growth, development, immunity and environmental …
Nitric oxide and peroxynitrite in health and disease
P Pacher, JS Beckman, L Liaudet - Physiological reviews, 2007 - journals.physiology.org
The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …
[HTML][HTML] Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription
Parkinson's disease (PD) is characterized by loss of A9 dopaminergic (DA) neurons in the
substantia nigra pars compacta (SNpc). An association has been reported between PD and …
substantia nigra pars compacta (SNpc). An association has been reported between PD and …
S-nitrosylation of Drp1 mediates β-amyloid-related mitochondrial fission and neuronal injury
Mitochondria continuously undergo two opposing processes, fission and fusion. The
disruption of this dynamic equilibrium may herald cell injury or death and may contribute to …
disruption of this dynamic equilibrium may herald cell injury or death and may contribute to …
Synaptic plasticity: LTP and LTD
MF Bear, RC Malenka - Current opinion in neurobiology, 1994 - Elsevier
Long-term potentiation (LTP) is a synaptic enhancement that follows brief, high-frequency
electrical stimulation in the hippocampus and neocortex. Recent evidence suggests that …
electrical stimulation in the hippocampus and neocortex. Recent evidence suggests that …
Biochemistry of nitric oxide and its redox-activated forms
Nitric oxide (NO⋅), a potentially toxic molecule, has been implicated in a wide range of
biological functions. Details of its biochemistry, however, remain poorly understood. The …
biological functions. Details of its biochemistry, however, remain poorly understood. The …
A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds
CONGENERS of nitrogen monoxide (NO) are neuroprotective and neurodestructive1–7. To
address this apparent paradox, we considered the effects on neurons of compounds …
address this apparent paradox, we considered the effects on neurons of compounds …
Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle
VM Bolotina, S Najibi, JJ Palacino, PJ Pagano… - Nature, 1994 - nature.com
NITRIC oxide is the major endothelium-derived relaxing factor (EDRF) 1–3, and it is thought
to relax smooth muscle cells by stimulation of guanylate cyclase, accumulation of its product …
to relax smooth muscle cells by stimulation of guanylate cyclase, accumulation of its product …
Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell …
E Bonfoco, D Krainc, M Ankarcrona… - Proceedings of the …, 1995 - National Acad Sciences
N-Methyl-D-aspartate (NMDA) receptor-mediated neurotoxicity may depend, in part, on the
generation of nitric oxide (NO.) and superoxide anion (O2.-), which react to form peroxynitrite …
generation of nitric oxide (NO.) and superoxide anion (O2.-), which react to form peroxynitrite …