Severe respiratory syncytial virus infection in children: burden, management, and emerging therapies

NI Mazur, MT Caballero, MC Nunes - The Lancet, 2024 - thelancet.com
The global burden of respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI)
in young children is high. The RSV prevention strategies approved in 2023 will be essential …

Lower respiratory tract infection caused by respiratory syncytial virus: current management and new therapeutics

NI Mazur, F Martinón-Torres, E Baraldi… - The Lancet …, 2015 - thelancet.com
Respiratory syncytial virus (RSV) is a major worldwide cause of morbidity and mortality in
children under five years of age. Evidence-based management guidelines suggest that …

Eviction, health inequity, and the spread of COVID-19: housing policy as a primary pandemic mitigation strategy

EA Benfer, D Vlahov, MY Long, E Walker-Wells… - Journal of Urban …, 2021 - Springer
The COVID-19 pandemic precipitated catastrophic job loss, unprecedented unemployment
rates, and severe economic hardship in renter households. As a result, housing precarity …

Respiratory syncytial virus infection during infancy and asthma during childhood in the USA (INSPIRE): a population-based, prospective birth cohort study

C Rosas-Salazar, T Chirkova, T Gebretsadik… - The Lancet, 2023 - thelancet.com
Background Early-life severe respiratory syncytial virus (RSV) infection has been associated
with the onset of childhood wheezing illnesses. However, the relationship between RSV …

Evaluating the next generation of RSV intervention strategies: a mathematical modelling study and cost-effectiveness analysis

D Hodgson, R Pebody, J Panovska-Griffiths… - BMC medicine, 2020 - Springer
Background With a suite of promising new RSV prophylactics on the horizon, including long-
acting monoclonal antibodies and new vaccines, it is likely that one or more of these will …

[HTML][HTML] Optimal respiratory syncytial virus intervention programmes using nirsevimab in England and Wales

D Hodgson, M Koltai, F Krauer, S Flasche, M Jit… - Vaccine, 2022 - Elsevier
Abstract Introduction Respiratory Syncytial Virus (RSV) is a major cause of acute lower
respiratory tract infections (ALRI) in infants. There are no licensed vaccines and only one …

Modeling respiratory syncytial virus adult vaccination in the United States with a dynamic transmission model

T Van Effelterre, N Hens, LJ White… - Clinical Infectious …, 2023 - academic.oup.com
Background Respiratory syncytial virus (RSV) is shown to cause substantial morbidity,
hospitalization, and mortality in infants and older adults. Population-level modeling of RSV …

[HTML][HTML] Determinants of RSV epidemiology following suppression through pandemic contact restrictions

M Koltai, F Krauer, D Hodgson, E van Leeuwen… - Epidemics, 2022 - Elsevier
Introduction COVID-19 related non-pharmaceutical interventions (NPIs) led to a suppression
of RSV circulation in winter 2020/21 in the UK and an off-season resurgence in Summer …

Respiratory syncytial virus (RSV) neutralizing antibodies at birth predict protection from RSV illness in infants in the first 3 months of life

AG Buchwald, BS Graham, A Traore… - Clinical Infectious …, 2021 - academic.oup.com
Background Respiratory syncytial virus (RSV) is a leading cause of viral pneumonia and
bronchiolitis during the first 6 months of life. Placentally transferred antibodies can prevent …

Effectiveness and cost-effectiveness of RSV infant and maternal immunization programs: A case study of Nunavik, Canada

S Nourbakhsh, A Shoukat, K Zhang, G Poliquin… - …, 2021 - thelancet.com
Background Despite passive immunization with palivizumab to select high-risk children
under two years of age, the health and economic burden of respiratory syncytial virus (RSV) …