Neuroligin-2 as a central organizer of inhibitory synapses in health and disease
H Ali, L Marth, D Krueger-Burg - Science Signaling, 2020 - science.org
Postsynaptic organizational protein complexes play central roles both in orchestrating
synapse formation and in defining the functional properties of synaptic transmission that …
synapse formation and in defining the functional properties of synaptic transmission that …
Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia
We conducted a genome-wide association study (GWAS) with replication in 36,180 Chinese
individuals and performed further transancestry meta-analyses with data from the Psychiatry …
individuals and performed further transancestry meta-analyses with data from the Psychiatry …
The role of cell adhesion molecule IgSF9b at the inhibitory synapse and psychiatric disease
JD Clarin, N Reddy, C Alexandropoulos… - … & Biobehavioral Reviews, 2024 - Elsevier
Understanding perturbations in synaptic function between health and disease states is
crucial to the treatment of neuropsychiatric illness. While genome-wide association studies …
crucial to the treatment of neuropsychiatric illness. While genome-wide association studies …
[PDF][PDF] Long neural genes harbor recurrent DNA break clusters in neural stem/progenitor cells
Repair of DNA double-strand breaks (DSBs) by non-homologous end joining is critical for
neural development, and brain cells frequently contain somatic genomic variations that …
neural development, and brain cells frequently contain somatic genomic variations that …
Personalized immunotherapy against several neuronal and brain tumors
S Kuttruff-coqui, T Weinschenk, J Fritsche… - US Patent …, 2021 - Google Patents
2014-11-12 Assigned to IMMATICS BIOTECHNOLOGIES GMBH reassignment IMMATICS
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
Genetic predictors of antipsychotic response to lurasidone identified in a genome wide association study and by schizophrenia risk genes
J Li, A Yoshikawa, MD Brennan, TL Ramsey… - Schizophrenia …, 2018 - Elsevier
Biomarkers which predict response to atypical antipsychotic drugs (AAPDs) increases their
benefit/risk ratio. We sought to identify common variants in genes which predict response to …
benefit/risk ratio. We sought to identify common variants in genes which predict response to …
Differential cognitive performances between schizophrenic responders and non-responders to antipsychotics: correlation with course of the illness, psychopathology …
A de Bartolomeis, R Balletta, S Giordano… - Psychiatry …, 2013 - Elsevier
Multiple lines of evidence demonstrate that schizophrenia patients may perform worse than
normal controls in several cognitive tasks. However, little is known on putative differences in …
normal controls in several cognitive tasks. However, little is known on putative differences in …
Prioritization of disease genes from GWAS using ensemble-based positive-unlabeled learning
A primary challenge in understanding disease biology from genome-wide association
studies (GWAS) arises from the inability to directly implicate causal genes from association …
studies (GWAS) arises from the inability to directly implicate causal genes from association …
The influence of the glutamatergic system on cognition in schizophrenia: a systematic review
Previous literature showing the role of the glutamatergic system on cognition in
schizophrenia has been inconclusive. 44 relevant pharmacological, candidate gene and …
schizophrenia has been inconclusive. 44 relevant pharmacological, candidate gene and …
Treatment-resistant schizophrenia: Addressing white matter integrity, intracortical glutamate levels, clinical and cognitive profiles between early-and adult-onset …
M Matrone, GD Kotzalidis, A Romano, A Bozzao… - Progress in Neuro …, 2022 - Elsevier
Background Treatment-resistance in schizophrenia is 30–40%. Its neurobiology remains
unclear; to explore it, we conducted a combined spectrometry/tractography/cognitive battery …
unclear; to explore it, we conducted a combined spectrometry/tractography/cognitive battery …