The epigenome in neurodevelopmental disorders

J Reichard, G Zimmer-Bensch - Frontiers in Neuroscience, 2021 - frontiersin.org
Neurodevelopmental diseases (NDDs), such as autism spectrum disorders, epilepsy, and
schizophrenia, are characterized by diverse facets of neurological and psychiatric …

Signaling from axon guidance receptors

GJ Bashaw, R Klein - Cold Spring Harbor perspectives …, 2010 - cshperspectives.cshlp.org
Determining how axon guidance receptors transmit signals to allow precise pathfinding
decisions is fundamental to our understanding of nervous system development and may …

Development of continuous and discrete neural maps

L Luo, JG Flanagan - Neuron, 2007 - cell.com
Two qualitatively different kinds of neural map have been described: continuous maps
exemplified by the visual retinotopic map, and discrete maps exemplified by the olfactory …

Integrative mechanisms of oriented neuronal migration in the developing brain

I Evsyukova, C Plestant, ES Anton - Annual review of cell and …, 2013 - annualreviews.org
The emergence of functional neuronal connectivity in the developing cerebral cortex
depends on neuronal migration. This process enables appropriate positioning of neurons …

Eph-dependent cell-cell adhesion and segregation in development and cancer

E Nievergall, M Lackmann, PW Janes - Cellular and Molecular Life …, 2012 - Springer
Numerous studies attest to essential roles for Eph receptors and their ephrin ligands in
controlling cell positioning and tissue patterning during normal and oncogenic development …

Molecules and mechanisms involved in the generation and migration of cortical interneurons

LR Hernández-Miranda, JG Parnavelas… - ASN neuro, 2010 - journals.sagepub.com
The GABA (γ-aminobutyric acid)-containing interneurons of the neocortex are largely
derived from the ganglionic eminences in the subpallium. Numerous studies have …

Ephrin‐A5 acts as a repulsive cue for migrating cortical interneurons

G Zimmer, P Garcez, J Rudolph… - European Journal of …, 2008 - Wiley Online Library
Cortical interneurons are born in the germinative zones of the ganglionic eminences in the
subpallium, and migrate tangentially in spatially and temporally well‐defined corridors into …

Bidirectional ephrinB3/EphA4 signaling mediates the segregation of medial ganglionic eminence-and preoptic area-derived interneurons in the deep and superficial …

G Zimmer, J Rudolph, J Landmann… - Journal of …, 2011 - Soc Neuroscience
The integration of interneuron subtypes into specific microcircuits is essential for proper
cortical function. Understanding to what extent interneuron diversity is regulated and …

EphrinA5 regulates cell motility by modulating Snhg15/DNA triplex-dependent targeting of DNMT1 to the Ncam1 promoter

CB Yildiz, T Kundu, J Gehrmann, J Koesling… - Epigenetics & …, 2023 - Springer
Cell–cell communication is mediated by membrane receptors and their ligands, such as the
Eph/ephrin system, orchestrating cell migration during development and in diverse cancer …

Role of DNMTs in the Brain

CB Yildiz, G Zimmer-Bensch - DNA Methyltransferases-Role and Function, 2022 - Springer
DNA methyltransferases (DNMTs) are widely expressed in the brain, dictating the
transcriptional activity of genes through various epigenetic mechanisms. Functional …