Advances about immunoinflammatory pathogenesis and treatment in diabetic peripheral neuropathy

T Xue, X Zhang, Y Xing, S Liu, L Zhang… - Frontiers in …, 2021 - frontiersin.org
Most diabetic patients develop diabetic peripheral neuropathy (DPN). DPN is related to the
increase of inflammatory cells in peripheral nerves, abnormal cytokine expression, oxidative …

[HTML][HTML] Research progress of active ingredients of Scutellaria baicalensis in the treatment of type 2 diabetes and its complications

W Yingrui, L Zheng, L Guoyan, W Hongjie - Biomedicine & …, 2022 - Elsevier
Diabetes mellitus is a common disorder of endocrine and metabolic disorders. Long term
hyperglycemia can lead to a variety of serious chronic complications, such as diabetic …

Challenging directions in pediatric diabetes-the place of oxidative stress and antioxidants in systemic decline

VV Lupu, I Miron, LM Trandafir, E Jechel… - Frontiers in …, 2024 - frontiersin.org
Diabetes is a complex condition with a rising global incidence, and its impact is equally
evident in pediatric practice. Regardless of whether we are dealing with type 1 or type 2 …

Diabetes mellitus: endotheldiszfunkció és haemostasiselváltozások= Diabetes mellitus: endothelial dysfunction and changes in hemostasis

B Babik, F Peták, S Agócs, I Blaskovics, E Alács… - Orvosi hetilap, 2018 - real.mtak.hu
Absztrakt: A diabetes mellitus magas vércukorszinttel járó krónikus metabolikus
kórelváltozások heterogén csoportját jelöli. A diabetes az élethosszig tartó kezelés …

Application of high-resolution ultrasound on diagnosing diabetic peripheral neuropathy

H Huang, S Wu - Diabetes, Metabolic Syndrome and Obesity, 2021 - Taylor & Francis
Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus (DM).
The typical manifestation is a length-dependent “glove and sock” sensation. At present …

Ellagic acid inhibits high glucose‑induced injury in rat mesangial cells via the PI3K/Akt/FOXO3a signaling pathway

W Lin, G Liu, X Kang, P Guo… - Experimental and …, 2021 - spandidos-publications.com
The pathological damage of mesangial cells serves an important role in the occurrence and
development of diabetic nephropathy. Ellagic acid has been reported to possess …

Celecoxib ameliorates diabetic neuropathy by decreasing apoptosis and oxidative stress in dorsal root ganglion neurons via the miR‑155/COX‑2 axis

X Cheng, L Zhao, T Ke, X Wang… - Experimental and …, 2021 - spandidos-publications.com
Celecoxib (CXB) is the only clinical cyclooxygenase‑2 (COX‑2) inhibitor. Oral administration
of CXB in experimental diabetic mice effectively relieved the symptoms of diabetic …

Current Concepts in the Molecular Mechanisms and Management of Diabetic Neuropathy by Pharmacotherapeutics and Natural Compounds

Shivam, AK Gupta, S Kumar - Central Nervous System Agents …, 2024 - benthamdirect.com
One of the most crippling effects of diabetes mellitus is diabetic neuropathy, which can
cause discomfort, loss of movement, and even amputation. Diabetic neuropathy manifests in …

Alpha-lipoic Acid suppresses P2X receptor activities and visceral hypersensitivity to colorectal distention in diabetic rats

J Hu, X Qin, ZY Song, PP Yang, Y Feng, Q Sun… - Scientific reports, 2017 - nature.com
The present study was designed to investigate the roles of P2X3 receptors in dorsal root
ganglion (DRG) neurons in colonic hypersensitivity and the effects of alpha-lipoic acid (ALA) …

Sensitivity and specificity of high frequency ultrasound score (DCEC) in diabetic peripheral neuropathy

H Huang, C Tang, M Li, J Huang, Y Li, S Wu - Journal of Diabetes & …, 2022 - Springer
Objectives To summarize the ultrasonic characteristics of peripheral nerve damage in type 2
diabetes and to verify the diagnostic value of DCEC score for DPN. Methods A total of 289 …