Spatiotemporal firing patterns in the cerebellum

CI De Zeeuw, FE Hoebeek, LWJ Bosman… - Nature Reviews …, 2011 - nature.com
Neurons are generally considered to communicate information by increasing or decreasing
their firing rate. However, in principle, they could in addition convey messages by using …

A systematic review of direct outputs from the cerebellum to the brainstem and diencephalon in mammals

M Novello, LWJ Bosman, CI De Zeeuw - The Cerebellum, 2024 - Springer
The cerebellum is involved in many motor, autonomic and cognitive functions, and new
tasks that have a cerebellar contribution are discovered on a regular basis. Simultaneously …

Cerebellar nuclei evolved by repeatedly duplicating a conserved cell-type set

JM Kebschull, EB Richman, N Ringach, D Friedmann… - Science, 2020 - science.org
INTRODUCTION The brains of extant animals have evolved over hundreds of millions of
years from simple circuits. Cell types diversified, connections elaborated, and new brain …

Modular output circuits of the fastigial nucleus for diverse motor and nonmotor functions of the cerebellar vermis

H Fujita, T Kodama, S Du Lac - Elife, 2020 - elifesciences.org
The cerebellar vermis, long associated with axial motor control, has been implicated in a
surprising range of neuropsychiatric disorders and cognitive and affective functions …

Brainstem neurons that command mammalian locomotor asymmetries

JM Cregg, R Leiras, A Montalant, P Wanken… - Nature …, 2020 - nature.com
Descending command neurons instruct spinal networks to execute basic locomotor
functions, such as gait and speed. The command functions for gait and speed are symmetric …

Diverse inhibitory projections from the cerebellar interposed nucleus

EN Judd, SM Lewis, AL Person - Elife, 2021 - elifesciences.org
The cerebellum consists of parallel circuit modules that contribute to diverse behaviors,
spanning motor to cognitive. Recent work employing cell-type-specific tracing has identified …

Excitatory cerebellar nucleocortical circuit provides internal amplification during associative conditioning

Z Gao, M Proietti-Onori, Z Lin, MM Ten Brinke… - Neuron, 2016 - cell.com
Closed-loop circuitries between cortical and subcortical regions can facilitate precision of
output patterns, but the role of such networks in the cerebellum remains to be elucidated …

Cerebellum lecture: the cerebellar nuclei—core of the cerebellum

JM Kebschull, F Casoni, GG Consalez, D Goldowitz… - The Cerebellum, 2024 - Springer
The cerebellum is a key player in many brain functions and a major topic of neuroscience
research. However, the cerebellar nuclei (CN), the main output structures of the cerebellum …

Microglia-triggered plasticity of intrinsic excitability modulates psychomotor behaviors in acute cerebellar inflammation

M Yamamoto, M Kim, H Imai, Y Itakura, G Ohtsuki - Cell reports, 2019 - cell.com
Cerebellar dysfunction relates to various psychiatric disorders, including autism spectrum
and depressive disorders. However, the physiological aspect is less advanced. Here, we …

Cerebellar modulation of synaptic input to freezing-related neurons in the periaqueductal gray

CE Vaaga, ST Brown, IM Raman - elife, 2020 - elifesciences.org
Innate defensive behaviors, such as freezing, are adaptive for avoiding predation. Freezing-
related midbrain regions project to the cerebellum, which is known to regulate rapid …