Sperm selection in natural conception: what can we learn from Mother Nature to improve assisted reproduction outcomes?

D Sakkas, M Ramalingam, N Garrido… - Human reproduction …, 2015 - academic.oup.com
BACKGROUND In natural conception only a few sperm cells reach the ampulla or the site of
fertilization. This population is a selected group of cells since only motile cells can pass …

The combined human sperm proteome: cellular pathways and implications for basic and clinical science

A Amaral, J Castillo, J Ramalho-Santos… - Human reproduction …, 2014 - academic.oup.com
BACKGROUND The human sperm cell is very well suited for proteomic studies, as it is
accessible, can be easily purified and is believed to be transcriptionally and translationally …

The contribution of human sperm proteins to the development and epigenome of the preimplantation embryo

J Castillo, M Jodar, R Oliva - Human reproduction update, 2018 - academic.oup.com
BACKGROUND Knowledge of the proteomic composition of the gametes is essential to
understand reproductive functions. Most of the sperm proteins are related to …

Semen proteomics and male infertility

M Jodar, A Soler-Ventura, R Oliva… - Journal of …, 2017 - Elsevier
Semen is a complex body fluid containing an admixture of spermatozoa suspended in
secretions from the testes and epididymis which are mixed at the time of ejaculation with …

Human sperm tail proteome suggests new endogenous metabolic pathways

A Amaral, J Castillo, JM Estanyol, JL Ballescà… - Molecular & Cellular …, 2013 - ASBMB
Proteomic studies are contributing greatly to our understanding of the sperm cell, and more
detailed descriptions are expected to clarify additional cellular and molecular sperm …

Identification of proteins involved in human sperm motility using high-throughput differential proteomics

A Amaral, C Paiva, C Attardo Parrinello… - Journal of Proteome …, 2014 - ACS Publications
Mammalian sperm motility is a prerequisite for in vivo fertilization, and alterations in this
parameter are commonly observed in infertile males. However, we still do not have a …

In-depth proteomic analysis of the human sperm reveals complex protein compositions

G Wang, Y Guo, T Zhou, X Shi, J Yu, Y Yang, Y Wu… - Journal of …, 2013 - Elsevier
The male gamete (sperm) can fertilize an egg, and pass the male genetic information to the
offspring. It has long been thought that sperm had a simple protein composition. Efforts have …

Identification of protein changes in human spermatozoa throughout the cryopreservation process

OA Bogle, K Kumar, C Attardo‐Parrinello… - …, 2017 - Wiley Online Library
Cryoinjury is a consequence of cryopreservation and may have a negative impact on sperm
quality regarding motility, morphology, and viability. This study was designed to identify …

Insights into the sperm chromatin and implications for male infertility from a protein perspective

A de la Iglesia, M Jodar, R Oliva… - WIREs Mechanisms of …, 2023 - Wiley Online Library
Male germ cells undergo an extreme but fascinating process of chromatin remodeling that
begins in the testis during the last phase of spermatogenesis and continues through …

Fertility management of bulls to improve beef cattle productivity

JC Thundathil, AL Dance, JP Kastelic - Theriogenology, 2016 - Elsevier
Global demand for animal proteins is increasing, necessitating increased efficiency of global
food production. Improving reproductive efficiency of beef cattle, especially bull fertility, is …