Abstract TGA2 and NONEXPRESSER OF PR GENES1 (NPR1) are activators of systemic
acquired resistance (SAR) and of the SAR marker gene pathogenesis-related-1 (PR-1) in …

Assembly of the RNA-induced silencing complex (RISC) consists of loading duplex (guide–
passenger) siRNA onto Argonaute (Ago2) and removing the passenger strand. Ago2 …

Trax–translin heteromers, also known as C3PO, have been proposed to activate the RNA-
induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA …

RNA interference (RNAi), an RNA-dependent gene silencing process that is initiated by
double-stranded RNA (dsRNA) molecules, has been applied with variable success in …

Translin and its interacting partner protein, TRAX, are members of the translin superfamily.
These proteins are involved in mRNA regulation and in promoting RISC activity by removing …

Translin and TRAX proteins play roles in very important cellular processes such as DNA
recombination, spatial and temporal expression of mRNA, and in siRNA processing …

Translin, a highly conserved, DNA/RNA binding protein, is abundantly expressed in brain,
testis and in certain malignancies. It was discovered initially in the quest to find proteins that …

Main conclusion For the first time, a plant (rice) translin was characterized. The rice translin
protein, which was octameric in native state, bound efficiently to single-stranded DNA and …

Crystals of native Drosophila melanogaster translin diffracted to 7 Å resolution. Reductive
methylation of the protein improved crystal quality. The native and methylated proteins …

Internal factors and external agents are a source of constant genomic stress in living organ‐-
isms leading to instability in the form of chromosomal deletions, duplications and transloca …