Large animal models in regenerative medicine and tissue engineering: to do or not to do

I Ribitsch, PM Baptista, A Lange-Consiglio… - … in Bioengineering and …, 2020 - frontiersin.org
Rapid developments in Regenerative Medicine and Tissue Engineering has witnessed an
increasing drive toward clinical translation of breakthrough technologies. However, the …

[HTML][HTML] Models of osteoarthritis: the good, the bad and the promising

PJ Cope, K Ourradi, Y Li, M Sharif - Osteoarthritis and cartilage, 2019 - Elsevier
Osteoarthritis (OA) is a chronic degenerative disease of diarthrodial joints most commonly
affecting people over the age of forty. The causes of OA are still unknown and there is much …

The human meniscus: a review of anatomy, function, injury, and advances in treatment

AJS Fox, F Wanivenhaus, AJ Burge… - Clinical …, 2015 - Wiley Online Library
Meniscal injuries are recognized as a cause of significant musculoskeletal morbidity. The
menisci are vital for the normal function and long‐term health of the knee joint. The purpose …

Animal models of osteoarthritis: comparisons and key considerations

AM McCoy - Veterinary pathology, 2015 - journals.sagepub.com
Osteoarthritis (OA) is unquestionably one of the most important chronic health issues in
humans, affecting millions of individuals and costing billions of dollars annually. Despite …

3D cell-printing of biocompatible and functional meniscus constructs using meniscus‐derived bioink

S Chae, SS Lee, YJ Choi, G Gao, JH Wang, DW Cho - Biomaterials, 2021 - Elsevier
Meniscus injuries are prevalent in orthopedic diagnosis. The reconstruction of the structural
inhomogeneity and anisotropy of the meniscus is a major challenge in clinical practice …

A review of translational animal models for knee osteoarthritis

MH Gregory, N Capito, K Kuroki, AM Stoker, JL Cook… - …, 2012 - Wiley Online Library
Knee osteoarthritis remains a tremendous public health concern, both in terms of health‐
related quality of life and financial burden of disease. Translational research is a critical step …

Meniscal repair: the current state and recent advances in augmentation

S Bansal, ER Floyd, MA Kowalski… - Journal of …, 2021 - Wiley Online Library
Meniscal injuries represent one of the most common orthopedic injuries. The most frequent
treatment is partial resection of the meniscus, or meniscectomy, which can affect joint …

[HTML][HTML] Repetitive allogeneic intraarticular injections of synovial mesenchymal stem cells promote meniscus regeneration in a porcine massive meniscus defect …

D Hatsushika, T Muneta, T Nakamura, M Horie… - Osteoarthritis and …, 2014 - Elsevier
Objective A new strategy is required in order to regenerate a meniscus for extensive defects.
Synovial mesenchymal stem cells (MSCs) are an attractive cell source for meniscus …

Meniscus repair and regeneration: review on current methods and research potential

C Scotti, MT Hirschmann, P Antinolfi, I Martin… - European cells & …, 2013 - air.unimi.it
A laser-illuminated Fabry-Perot cavity with a finesse of 83000 and power dissipation of a few
μW is tested at room temperature. The sensitivity to changes in the length of the cavity is …

Riboflavin-induced photo-crosslinking of collagen hydrogel and its application in meniscus tissue engineering

J Heo, RH Koh, W Shim, HD Kim, HG Yim… - Drug delivery and …, 2016 - Springer
A meniscus tear is a common knee injury, but its regeneration remains a clinical challenge.
Recently, collagen-based scaffolds have been applied in meniscus tissue engineering …