Recent advances and application of whole genome amplification in molecular diagnosis and medicine

X Wang, Y Liu, H Liu, W Pan, J Ren, X Zheng… - MedComm, 2022 - Wiley Online Library
Whole genome amplification (WGA) is a technology for non‐selective amplification of the
whole genome sequence, first appearing in 1992. Its primary purpose is to amplify and …

Effects of UGT2B7 rs7662029 and rs7439366 polymorphisms on sublingual buprenorphine metabolism in heroin addicts: An improved PCR-RFLP assay for the …

D Kaya-Akyüzlü, S Özkan-Kotiloğlu, C Bal… - Environmental …, 2022 - Elsevier
This study aimed to determine the effects of UGT2B7 rs7662029 and rs7439366
polymorphisms on plasma buprenorphine (BUP) concentration and different treatment …

Association of DRD2 gene polymorphisms with schizophrenia in the young Bangladeshi population: A pilot study

MS Hussain, SA Siddiqui, S Mondal, MS Millat… - Heliyon, 2020 - cell.com
Purpose DRD2 gene is considered one of the most important candidate genes for the
schizophrenia (SCZ) development due to its role in dopamine signaling and no genetic …

Application of CRS‐PCR‐RFLP to identify CYP1A1 gene polymorphism

M Ding, X Duan, X Feng, P Wang… - Journal of Clinical …, 2017 - Wiley Online Library
Background Cytochrome P4501A1 (CYP 1A1) is a member of the cytochrome P450 gene
family and plays an important role in the metabolism of exogenous and endogenous …

An improved PCR‐CTPP assay for the detection of ADH 1B Arg48His polymorphism

S Jiang, Y Tong, R Zhao, G Xiong… - Journal of clinical …, 2018 - Wiley Online Library
Background ADH 1B Arg48His polymorphism is associated with the development of alcohol‐
related diseases. In this study, we aimed to explore an improved polymerase chain reaction …

Association between APE1 ASP148GLU and colorectal cancer risk: a meta-analysis

C Lin, Y Jin, S Cheng, W Wang - Clinical and Investigative …, 2020 - utpjournals.press
Background Colorectal cancer (CRC) is recognized as one of the most common cancer
globally. The association between CRC and apurinic endonuclease 1 (APE1) Asp148Glu …

首发精神分裂症与DRD2 基因多态性和认知功能的关系研究

董震, 刘欣, 张丽丽, 王素娟, 栗克清, 张云淑 - 中国全科医学, 2021 - chinagp.net
背景精神分裂症的发病机制与D2 受体(DRD2) 基因多态性有关, 其主要症状之一是认知功能
障碍, 认知功能又与精神分裂症的患病风险有关, 但目前关于首发精神分裂症与DRD2 …

Detecting the OPRK1 rs963549 and rs997917 Polymorphisms by Novel PCR-RFLP Methods and Determining Their Genotype/Allele Frequencies in a Turkish …

S Özkan-Kotiloğlu - Biology Bulletin, 2023 - Springer
Opioid receptor kappa (KOR) is one of three endogenous opioid receptors which has critical
roles in rewarding systems by promoting anti-reward effects and causes dysphoria and …

Detecting the polymorphism of TERF1 gene by an improved PCR‐RFLP method

P Wang, Y Yang, S Wang, X Duan… - Journal of Clinical …, 2018 - Wiley Online Library
Background Polymerase chain reaction‐restriction fragment length polymorphism (PCR‐
RFLP) is a common and mature method of detecting the single nucleotide polymorphism …

GHSR rs2232165 Gen Polimorfizminin Genotiplendirilmesi için PCR-RFLP yönteminin optimizasyonu ve Türk erkeklerinde alel frekansının belirlenmesi

S Özkan Kotiloğlu, D Kaya Akyüzlü, G Düzgün… - 2022 - acikerisim.aku.edu.tr
Çağımızın ciddi sorunlardan biri olan alkol bağımlılığı, genetik, çevresel, kültürel, gelişimsel
ve nörobiyolojik faktörlerin etkisiyle ortaya çıkmaktadır. Son yıllarda yeme davranışı …