Inflammatory conditions in selected organs increase the risk of cancer. An inflammatory
component is present also in the microenvironment of tumors that are not epidemiologically …

DNA damage and repair are linked to cancer. DNA damage that is induced endogenously or
from exogenous sources has the potential to result in mutations and genomic instability if not …

Gastric cancer is the sixth most commonly diagnosed cancer and the fourth leading cause of
cancer death worldwide. Helicobacter pylori (H. pylori) is one of the main risk factors for this …

Loss of DNA mismatch repair (MMR) function, due to somatic or germline epi/genetic
alterations of MMR genes leads to the accumulation of numerous mutations across the …

Abstract Background Paradoxically, Helicobacter pylori–positive (HP+) advanced gastric
cancer patients have a better prognosis than those who are HP–negative (HP-) …

The discovery that Helicobacter pylori is associated with gastric cancer has led to numerous
studies that investigate the mechanisms by which H. pylori induces carcinogenesis. Gastric …

Helicobacter pylori infection of the human stomach is associated with inflammation that
leads to the release of reactive oxygen and nitrogen species (RONs), eliciting DNA damage …

Inflammation, among environmental risk factors, is one of the most important contributors to
colorectal cancer (CRC) development. In this way, studies revealed that the incidence of …

Over the last years, intensive investigations in molecular biology and cell physiology
extended tremendously the knowledge about the association of inflammation and cancer. In …

Gastric cancers are the third leading cause of cancer mortality in the world. Helicobacter
pylori causes over 60% of all stomach cancers. Colonization of the gastric mucosa by H …