Mapping, modeling, and characterization of protein–protein interactions on a proteomic scale

TM Cafarelli, A Desbuleux, Y Wang, SG Choi… - Current Opinion in …, 2017 - Elsevier
Highlights•Protein-protein interaction (PPI) mapping at proteome-scale provides a global
view of cellular organization and function.•Of the various methods for identifying PPIs, only …

Protein complexes, big data, machine learning and integrative proteomics: lessons learned over a decade of systematic analysis of protein interaction networks

PC Havugimana, P Hu, A Emili - Expert review of proteomics, 2017 - Taylor & Francis
Overview: Elucidation of the networks of physical (functional) interactions present in cells
and tissues is fundamental for understanding the molecular organization of biological …

Proteomic changes occurring along gonad maturation in the edible sea urchin Paracentrotus lividus

S Ghisaura, B Loi, G Biosa, M Baroli, D Pagnozzi… - Journal of …, 2016 - Elsevier
The reproductive stage of Paracentrotus lividus strongly influences product quality that, in
turn, impacts significantly on the market price. Large, compact and sweet gonads are …

Mass spectrometry methods to study protein-metabolite interactions

H Guo, H Peng, A Emili - Expert opinion on drug discovery, 2017 - Taylor & Francis
ABSTRACT Introduction: To​​​​ understand and manipulate biochemical processes and
signaling pathways, the knowledge of endogenous protein-metabolite interactions would be …

Sequence divergence and functional specializations of the ancient spliceosomal SF3b: implications in flexibility and adaptations of the multi-protein complex

A Yazhini, N Srinivasan, S Sandhya - Frontiers in Genetics, 2022 - frontiersin.org
Multi-protein assemblies are complex molecular systems that perform highly sophisticated
biochemical functions in an orchestrated manner. They are subject to changes that are …

[PDF][PDF] Computational methods for exploratory analysis of proteomics data

W Aftab - 2022 - edoc.ub.uni-muenchen.de
With the emergence of the rapidly developing fields of omics and informatics, the 21st
century has seen extraordinary advances in biological sciences. Omics technologies …

[PDF][PDF] Andrew Emili, Ph. D.

A Emili - bu.edu
Dr. Emili is an internationally recognized leader in protein interaction networks and the
development of innovative technologies to systematically characterize protein complexes on …