Metal cations are associated with many biological processes. The effects of these cations on
nucleic acids and chromatin were extensively studied in the early stages of nucleic acid and …

Eukaryotic genomic DNA is combined with histones, nonhistone proteins, and RNA to form
chromatin, which is extensively packaged hierarchically to fit inside a cell's nucleus. The …

While most transcription factors exit the chromatin during mitosis and the genome becomes
silent, a subset of factors remains and “bookmarks” genes for rapid reactivation as cells …

Although it is believed that the interconversion between permissive and refractory chromatin
structures is important in regulating gene transcription, this process is poorly understood …

The folding of the chromatin filament and, in particular, the organization of genomic DNA
within metaphase chromosomes has attracted the interest of many laboratories during the …

Cryo‐electron tomography and small‐angle X‐ray scattering were used to investigate the
chromatin folding in metaphase chromosomes. The tomographic 3D reconstructions show …

The three-dimensional organization of tightly condensed chromatin within metaphase
chromosomes has been one of the most challenging problems in structural biology since the …

The first description of intrachromosomal fibers was made by Baranetzky in 1880. Since that
time, a plethora of fibrillar substructures have been described inside the mitotic …

Experimental evidence indicates that the chromatin filament is self‐organized into a
multilayer planar structure that is densely stacked in metaphase and unstacked in …

This perspective aims to identify the relationships between the structural and dynamic
properties of chromosomes and the fundamental properties of soft-matter systems …