Stroke is a leading cause of acquired, permanent disability worldwide. Although the
treatment of acute stroke has been improved considerably, the majority of patients to date …

After focal damage, cerebral networks reorganise their structural and functional anatomy to
compensate for both the lesion itself and remote effects. Novel developments in the analysis …

Restoration of human brain function after injury is a signal challenge for translational
neuroscience. Rodent stroke recovery studies identify an optimal or sensitive period for …

Reductions in blood flow to the brain of sufficient duration and extent lead to stroke, which
results in damage to neuronal networks and the impairment of sensation, movement or …

Ischemic damage to the brain triggers substantial reorganization of spared areas and
pathways, which is associated with limited, spontaneous restoration of function. A better …

Recent advances in analysis of brain signals, training patients to control these signals, and
improved computing capabilities have enabled people with severe motor disabilities to use …

Numerous studies argue that cortical reorganization may contribute to the restoration of
motor function following stroke. However, the evolution of changes during the post-stroke …

The brain has an intrinsic capacity to compensate for structural damage through
reorganizing of surviving networks. These processes are fundamental for recovery of …

Rodent stroke models provide the experimental backbone for the in vivo determination of the
mechanisms of cell death and neural repair, and for the initial testing of neuroprotective …

Stroke causes cell death but also birth and migration of new neurons within sites of ischemic
damage. The cellular environment that induces neuronal regeneration and migration after …