Atomic-resolution structural studies of membrane-associated proteins and peptides in a
membrane environment are important to fully understand their biological function and the …

New technologies for the purification of stable membrane proteins have emerged in recent
years, in particular methods that allow the preparation of membrane proteins with their …

Biological characterisation of membrane proteins lags behind that of soluble proteins. This
reflects issues with the traditional use of detergents for extraction, as the surrounding lipids …

Experimental characterization of membrane proteins often requires solubilization. A recent
approach is to use styrene-maleic acid (SMA) copolymers to isolate membrane proteins in …

The advent of amphiphilic copolymers enables integral membrane proteins to be solubilized
into stable 10–30 nm native nanodiscs to resolve their multisubunit structures, post …

The concept of a memtein as the minimal unit of membrane function is proposed here, and
refers to the complex of a membrane protein together with a continuous layer of biological …

Dopamine receptors (DRs) are class A G-Protein Coupled Receptors (GPCRs) prevalent in
the central nervous system (CNS). These receptors mediate physiological functions ranging …

Membrane proteins are notoriously difficult to investigate in isolation. The focus of this
chapter is the key step following extraction and purification of membrane proteins; namely …

Nanoparticles assembled with poly (styrene-maleic acid) copolymers, identified in the
literature as Lipodisq, SMALPs or Native Nanodisc, are routinely used as membrane …

The prognosis of pancreatic cancer is poor with the overall 5-year survival rate of less than
5% changing minimally over the past decades and future projections predicting it …