Heterocycles are an extraordinarily important class of compounds, making up more than half
of all known organic compounds. Heterocycles are present in a wide variety of drugs, most …

α-Haloketones play an essential role in the synthesis of complex N-, S-, O-heterocycles; of
which some exhibit a remarkable biological activity. Research further illustrated that α-bromo …

Precise control of the chemoselectivity of the halogenation of a substrate equipped with
multiple nucleophilic sites is highly demanding and challenging. Most reported chlorinations …

Conclusion This review reveals that the development of various convenient methods for the
selective synthesis of α-bromo carbonyl compounds in recent years. Many new brominating …

New process that can selectively prepare α, α-dichloro ketones from various ketones with 1,
3-dichloro-5, 5-dimethylhydantoin (DCDMH) using ammonium chloride as a catalyst is …

The degradation of geminal diazides is described. We show that diazido acetates are
converted into tetrazoles through the treatment with bases. The reaction of dichloro ketones …

The α-bromination of carbonyl compounds is one of the most important transformations and
also important precursors in synthetic organic chemistry. Particularly, the side chain …

An efficient and facile method is reported for the synthesis of a series of α, α-
dichloroketones. The direct dichlorination of methyl ketones and 1, 3-dicarbonyls using an …

An exceptionally efficient, environmentally safe and economic method has been developed
for regioselective α-bromination of various aralkyl ketones in excellent yield with N …

This review provides an overview of the recent literature on application of arylglyoxals the
synthesis of pyrrolo [2, 3-d] pyrimidines via multicomponent reactions in the period of 2008 …