COVID-19 convalescent plasma and clinical trials: understanding conflicting outcomes

D Focosi, M Franchini, L Pirofski… - Clinical microbiology …, 2022 - Am Soc Microbiol
Convalescent plasma (CP) recurs as a frontline treatment in epidemics because it is
available as soon as there are survivors. The COVID-19 pandemic represented the first …

Is SARS‐CoV‐2 viral clearance in nasopharyngeal swabs an appropriate surrogate marker for clinical efficacy of neutralising antibody‐based therapeutics?

D Focosi, M Franchini, L Pirofski… - Reviews in Medical …, 2022 - Wiley Online Library
Viral clearance is likely the best way to assess the efficacy of antibody‐based therapies.
Although antibodies can mediate a variety of effects that include modulation of inflammation …

COVID-19 convalescent plasma and randomized clinical trials: explaining conflicting outcomes and finding signals of efficacy

D Focosi, M Franchini, L Pirofski, T Burnouf, N Paneth… - medRxiv, 2021 - medrxiv.org
Convalescent plasma (CP) recurs as a frontline treatment in epidemics because it is
available as soon as there are survivors. The COVID-19 pandemic represented the first …

Mechanisms that could increase cancer vulnerability in COVID-19 mRNA vaccine recipients

P Azakarian - 2021 - osf.io
The BNT162b2 and mRNA-1273 vaccines have been rolled out globally in high numbers.
Even minimal risk groups have been fully vaccinated in many countries. We observe certain …