Aptamers are short, single-stranded oligonucleotides that bind to specific target molecules. The shape-forming feature of single-stranded oligonucleotides provides high affinity and …
K Strouhalova, M Přechová, A Gandalovičová… - Cancers, 2020 - mdpi.com
Intermediate filaments constitute the third component of the cellular skeleton. Unlike actin and microtubule cytoskeletons, the intermediate filaments are composed of a wide variety of …
F Danielsson, MKK Peterson, H Caldeira Araújo… - Cells, 2018 - mdpi.com
Vimentin is a protein that has been linked to a large variety of pathophysiological conditions, including cataracts, Crohn's disease, rheumatoid arthritis, HIV and cancer. Vimentin has also …
Vimentin is an intermediate filament protein that plays key roles in integration of cytoskeletal functions, and therefore in basic cellular processes such as cell division and migration …
Y Morita, M Leslie, H Kameyama, DE Volk, T Tanaka - Cancers, 2018 - mdpi.com
Aptamer-related technologies represent a revolutionary advancement in the capacity to rapidly develop new classes of targeting ligands. Structurally distinct RNA and DNA …
Conventional anticancer therapies, such as chemo-and/or radio-therapy are often unable to completely eradicate cancers due to abnormal tumor microenvironment, as well as …
Aptamers have a promising role in the field of life science and have been extensively researched for application as analytical tools, therapeutic agents and as vehicles for …
A Tabatabaee, B Nafari, A Farhang, A Hariri… - Cancer and Metastasis …, 2024 - Springer
This comprehensive review explores vimentin as a pivotal therapeutic target in cancer treatment, with a primary focus on mitigating metastasis and overcoming drug resistance …
Aptamers, also known as chemical antibodies, are single-stranded nucleic acid oligonucleotides which bind to their targets with high specificity and affinity. They are …