Post-translational modifications (PTMs) can occur on specific amino acids localized within
regulatory domains of target proteins, which control a protein's stability. These regions …

All eukaryotic organisms have evolved sophisticated immune systems to appropriately
respond to biotic stresses. In plants and animals, a key part of this immune system is pattern …

Protein phosphorylation is one of the most widespread post-translational modifications in
biology,. With advances in mass-spectrometry-based phosphoproteomics, 90,000 sites of …

Protein phosphorylation is a crucial regulator of protein and cellular function, yet, despite
identifying an enormous number of phosphorylation sites, the role of most is still unclear …

WebGestalt is a popular tool for the interpretation of gene lists derived from large scale-
omics studies. In the 2019 update, WebGestalt supports 12 organisms, 342 gene identifiers …

Protein phosphorylation is a key post-translational modification regulating protein function in
almost all cellular processes. Although tens of thousands of phosphorylation sites have …

Reversible protein phosphorylation is an important mechanism for regulating (dis) assembly
of biomolecular condensates. However, condensate-specific phosphosites remain largely …

Molecular alterations in cancer genes and associated signaling pathways are used to inform
new treatments for precision medicine in cancer. Small molecule inhibitors and monoclonal …

Proteomics, the study of all the proteins in biological systems, is becoming a data‐rich
science. Protein sequences and structures are comprehensively catalogued in online …

Protein phosphorylation dynamically integrates environmental and cellular information to
control biological processes. Identifying functional phosphorylation amongst the thousands …