Background: Since disulfiram's discovery in the 1940s and its FDA approval for alcohol use
disorder, other indications have been investigated. This review describes potential clinical …

The controversy regarding the underlying mechanisms of PTLDs and the increasingly bitter
debate over CLD, continues unabated over the past years. If anything, it has become more …

Lyme borreliosis affects the nervous system in three principal ways—mononuclear cell
meningitis, cranial neuropathies and radiculoneuropathies—the last a broad term …

Background Evidence‐based recommendations for treatment of Lyme neuroborreliosis
(LNB) should rely on the available literature. As new data emerges, close review and …

Lyme borreliosis or Lyme disease is the most frequently reported tick-borne disease in the
Northern Hemisphere. In countries of the Southern Hemisphere, such as Brazil, since the …

Background and purpose Residual symptoms after treatment of Lyme disease, sometimes
called post‐treatment Lyme disease symptoms (PTLDs), are a matter of ongoing …

As part of the NorthTick project, co-funded by the European Union through the European
Regional Development Fund and the North Sea Region Programme, specialists in the field …

Background Is there any basis for the apparent controversies surrounding Lyme disease? In
broad terms, the salient issues contributing are (1) the disconnect between a public view or …

Objective: Unusual clinical course Background: Lyme disease is a common tickborne
disease with a common presentation. Untreated Lyme disease can affect other organs. This …

In this issue of Infectious Disease Clinics of North America, guest editor Dr. Robert P. Smith
brings his considerable expertise to the topic of Lyme Disease and the Expanding Spectrum …