Cell surface remodeling by plasmin: a new function for an old enzyme

EI Deryugina, JP Quigley - BioMed Research International, 2012 - Wiley Online Library
Plasmin, one of the most potent and reactive serine proteases, is involved in various
physiological processes, including embryo development, thrombolysis, wound healing and …

Functional sites in the laminin alpha chains

N Suzuki, F Yokoyama, M Nomizu - Connective tissue research, 2005 - Taylor & Francis
Laminins, heterotrimers composed of α, β, and γ chains, are multifunctional glycoproteins
present in basement membranes. Laminins, the most important component of basement …

Laminin 5 mutations in junctional epidermolysis bullosa: molecular basis of Herlitz vs non-Herlitz phenotypes

A Nakano, SC Chao, L Pulkkinen, D Murrell… - Human genetics, 2002 - Springer
Junctional epidermolysis bullosa (JEB) is a group of heritable blistering diseases in which
tissue separation occurs within the lamina lucida of the cutaneous basement membrane …

Laminin-332-integrin interaction: a target for cancer therapy?

D Tsuruta, H Kobayashi, H Imanishi… - Current medicinal …, 2008 - ingentaconnect.com
For many years, extracellular matrix (ECM) was considered to function as a tissue support
and filler. However, we now know that ECM proteins control many cellular events through …

Biological function of laminin-5 and pathogenic impact of its deficiency

H Schneider, C Mühle, F Pacho - European journal of cell biology, 2007 - Elsevier
The basement membrane glycoprotein laminin-5 is a key component of the anchoring
complex connecting keratinocytes to the underlying dermis. It is secreted by keratinocytes as …

Cell type-specific differences in glycosaminoglycans modulate the biological activity of a heparin-binding peptide (RKRLQVQLSIRT) from the G domain of the laminin …

MP Hoffman, JA Engbring, PK Nielsen, J Vargas… - Journal of Biological …, 2001 - ASBMB
AG73 (RKRLQVQLSIRT), a peptide from the G domain of the laminin α1 chain, has diverse
biological activities with different cell types. The heparan sulfate side chains of syndecan-1 …

The tissue plasminogen activator-plasmin system participates in the rewarding effect of morphine by regulating dopamine release

T Nagai, K Yamada, M Yoshimura… - Proceedings of the …, 2004 - National Acad Sciences
Tissue plasminogen activator (tPA) is a serine protease that catalyzes the conversion of
plasminogen (plg) to plasmin, which in turn functions to degrade extracellular matrix proteins …

Survey of the year 2000 commercial optical biosensor literature

RL Rich, DG Myszka - Journal of Molecular Recognition, 2001 - Wiley Online Library
We have compiled a comprehensive list of the articles published in the year 2000 that
describe work employing commercial optical biosensors. Selected reviews of interest for the …

Microplasmin degrades fibronectin and laminin at vitreoretinal interface and outer retina during enzymatic vitrectomy

W Chen, W Mo, K Sun, X Huang, Y Zhang… - Current eye …, 2009 - Taylor & Francis
Purpose: To determine whether intravitreal administration of microplasmin (μPlm) will
degrade fibronectin (FN) and laminin (LN) in rat retina during μPlm-induced posterior …

Substrate stiffness regulates extracellular matrix deposition by alveolar epithelial cells

JL Eisenberg, A Safi, X Wei, HD Espinosa… - Research and reports …, 2011 - Taylor & Francis
Aim: The aim of the study was to address whether a stiff substrate, a model for pulmonary
fibrosis, is responsible for inducing changes in the phenotype of alveolar epithelial cells …