Leprosy: treatment, prevention, immune response and gene function

X Li, Y Ma, G Li, G Jin, L Xu, Y Li, P Wei… - Frontiers in …, 2024 - frontiersin.org
Since the leprosy cases have fallen dramatically, the incidence of leprosy has remained
stable over the past years, indicating that multidrug therapy seems unable to eradicate …

Understanding leprosy reactions and the impact on the lives of people affected: An exploration in two leprosy endemic countries

AI Putri, K de Sabbata, RI Agusni… - PLoS Neglected …, 2022 - journals.plos.org
Background Leprosy reactions, Type-1 and erythema nodosum leprosum, are immune-
mediated complications of leprosy, which play a significant role in the morbidity associated …

Mycobacterial infections in the hand and wrist

A Bachoura, DS Zelouf - Hand Clinics, 2020 - hand.theclinics.com
Background A majority of hand infections are caused by a few, yet common, gram-positive
cocci and gram-negative bacilli. These infections are characterized by significant …

Leprosy reactions and neuropathic pain in pure neural leprosy in a reference center in rio de janeiro–Brazil

IJR Pitta, MA Hacker, RT Vital, LR Andrade… - Frontiers in …, 2022 - frontiersin.org
Introduction Leprosy reactions are complications that can occur before, during, or after
multidrug therapy (MDT) and are considered a major cause of nerve damage. Neuritis is an …

Global epidemiology of leprosy from 2010 to 2020: A systematic review and meta-analysis of the proportion of sex, type, grade 2 deformity and age

J Yang, X Li, Y Sun, L Zhang, G Jin, G Li… - … and Global Health, 2022 - Taylor & Francis
The objectives of this study were to explore global epidemiological characteristics of leprosy,
and to provide reference for the construction of prevention strategies for leprosy. Computer …

Comparison of quality of life evaluated by SF‐36 and DLQI in multibacillary and paucibacillary leprosy patients from Sao Paulo, Brazil

R Guimenes Albuquerque… - International Journal …, 2019 - Wiley Online Library
Background Dermatological diseases have a negative impact on quality of life (QoL),
affecting mental and physical health. Leprosy patients usually present with a worse QoL …

Leprosy patients with deformities at post‐elimination stage: The Bangladesh experience

MR Mowla, DM Angkur, Z Hasan… - Skin Health and …, 2021 - Wiley Online Library
Background Disability assessment in leprosy patients is a very important factor in the
evaluation of the effectiveness of a leprosy elimination program. Little information exists on …

Body map stories from Colombia: experiences of people affected by leprosy and the influence of peers during diagnosis and treatment

MC Barbosa Ladino, C Jiménez Betancourth… - International Journal for …, 2024 - Springer
Introduction Almost one third of people affected by leprosy in Colombia suffer from disability,
which often results from delayed diagnosis and treatment. We aimed to explore the …

Case report: Myelitis and ganglionitis, an atypical presentation of Hansen's disease

CN Spitz, IJR Pitta, L Andrade, LB de Carvalho… - Frontiers in …, 2024 - frontiersin.org
Hansen's disease, or leprosy, is a disease characterized by dermatological and neurological
disorders. A neural form also exists, in which peripheral neuropathy occurs in the absence of …

Comparison of the efficacy and safety of minocycline and clofazimine in chronic and recurrent erythema nodosum leprosum—A randomized clinical trial

V Hanumanthu, V Thakur, T Narang… - Dermatologic …, 2021 - Wiley Online Library
Management of chronic/recurrent erythema nodosum leprosum (ENL) is challenging. The
majority of these patients become steroid‐dependent and suffer from the adverse effects of …