Oxidative stress (OS) is defined as a disturbance in the prooxidant‐antioxidant balance of
the cell, in favor of the former, which results in the antioxidant capacity of the cell to be …

During long standing hyperglycaemic state in diabetes mellitus, glucose forms covalent
adducts with the plasma proteins through a non-enzymatic process known as glycation …

Advanced glycation end products (AGEs) are mediators in the process of cellular
dysfunction in response to hyperglycemia. Numerous data indicate that the accumulation of …

The interplay between adipokines and pancreatic beta cells, often referred to as the adipo-
insular axis, plays a crucial role in regulating metabolic homeostasis. Adipokines are …

Obesity and type 2 diabetes mellitus (T2DM) are chronic pathologies with a high incidence
worldwide. They share some pathological mechanisms, including hyperinsulinemia, the …

Advanced glycation end products (AGEs) are a family of compounds of diverse chemical
nature that are the products of nonenzymatic reactions between reducing sugars and …

Obesity is associated with inflammation and type 2 diabetes. Innate immune system
comprised of cellular and molecular components plays an important role in the inflammatory …

Alpha-amylase (α-amylase) is a key player in the management of diabetes and its related
complications. This study was intended to have an insight into the binding of caffeic acid and …

An increase of visceral fat affects human bone health causing fragility, mechanical strength
reduction, and increased propensity to fractures because of impaired bone matrix …

Far beyond the compelling proofs supporting that the metabolic syndrome represents a risk
factor for diabetes and cardiovascular diseases, a growing body of evidence suggests that it …