Development of nanotechnology-mediated precision radiotherapy for anti-metastasis and radioprotection

Y Pan, W Tang, W Fan, J Zhang, X Chen - Chemical Society Reviews, 2022 - pubs.rsc.org
Radiotherapy (RT), including external beam RT and internal radiation therapy, uses high-
energy ionizing radiation to kill tumor cells. However, ionizing radiation inevitably damages …

Recent advances in cell penetrating peptide-based anticancer therapies

J Habault, JL Poyet - Molecules, 2019 - mdpi.com
Cell-penetrating-peptides (CPPs) are small amino-acid sequences characterized by their
ability to cross cellular membranes. They can transport various bioactive cargos inside cells …

[HTML][HTML] Review of the efficacy of nanoparticle-based drug delivery systems for cancer treatment

K Elumalai, S Srinivasan, A Shanmugam - Biomedical Technology, 2024 - Elsevier
This review evaluates the literature on nanoparticle-based drug delivery systems for cancer
treatment and assesses their efficacy. Nanoparticles have shown potential for improving …

Polymeric Nanoparticles for Drug Delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

[HTML][HTML] Drug resistance in metastatic breast cancer: tumor targeted nanomedicine to the rescue

V Gote, AR Nookala, PK Bolla, D Pal - International journal of molecular …, 2021 - mdpi.com
Breast cancer, specifically metastatic breast, is a leading cause of morbidity and mortality in
women. This is mainly due to relapse and reoccurrence of tumor. The primary reason for …

Recent advances in various stimuli-responsive hydrogels: From synthetic designs to emerging healthcare applications

A Roy, K Manna, S Pal - Materials Chemistry Frontiers, 2022 - pubs.rsc.org
With the development of broad interest in the synthesis of unique stimuli-responsive
materials and their various healthcare applications, stimuli-responsive hydrogels have …

[HTML][HTML] Drug delivery system based on magnetic iron oxide nanoparticles coated with (polyvinyl alcohol-zinc/aluminium-layered double hydroxide-sorafenib)

M Ebadi, K Buskaran, S Bullo, MZ Hussein… - Alexandria Engineering …, 2021 - Elsevier
The structural, physicochemical, morphological, and magnetic properties of magnetic drug
nanoparticles prepared using polymer, layered double hydroxide (LDHs) and drug as the …

Perspectives of using microRNA-loaded nanocarriers for epigenetic reprogramming of drug resistant colorectal cancers

OA Sukocheva, J Liu, ME Neganova… - Seminars in Cancer …, 2022 - Elsevier
Epigenetic regulation by microRNAs (miRs) demonstrated a promising therapeutic potential
of these molecules to regulate genetic activity in different cancers, including colorectal …

Insights into maleimide-thiol conjugation chemistry: Conditions for efficient surface functionalization of nanoparticles for receptor targeting

L Martínez-Jothar, S Doulkeridou, RM Schiffelers… - Journal of controlled …, 2018 - Elsevier
Maleimide-thiol chemistry is widely used for the design and preparation of ligand-decorated
drug delivery systems such as poly (lactide-co-glycolide)(PLGA) based nanoparticles (NPs) …

Learn from antibody–drug conjugates: consideration in the future construction of peptide-drug conjugates for cancer therapy

M Wu, W Huang, N Yang, Y Liu - Experimental Hematology & Oncology, 2022 - Springer
Cancer is one of the leading causes of death worldwide due to high heterogeneity. Although
chemotherapy remains the mainstay of cancer therapy, non-selective toxicity and drug …