Aptamers are short single-stranded nucleic acid sequences capable of binding to target
molecules in a way similar to antibodies. Due to various advantages such as prolonged …

Coined three decades ago, the term aptamer and directed evolution have now reached their
maturity. The concept that nucleic acid could modulate the activity of target protein as ligand …

We report a simple and rapid saliva‐based SARS‐CoV‐2 antigen test that utilizes a newly
developed dimeric DNA aptamer, denoted as DSA1N5, that specifically recognizes the spike …

First studies on thrombin-inhibiting DNA aptamers were reported in 1992, and since then a
large number of anticoagulant aptamers has been discovered. TBA–also named HD1, a 15 …

There is a significant need for rapid, cost-effective, and highly sensitive protein target
detection, particularly in the fields of food, environmental monitoring, and healthcare. The …

Multivalent interactions frequently occur in biological systems and typically provide higher
binding affinity and selectivity in target recognition than when only monovalent interactions …

Ochratoxin A (OTA) is one of the most common mycotoxins contaminating feed and
foodstuffs. Therefore, a great deal of concern is associated with AFB1 toxicity. In this work, a …

Multivalent aptamers that interact with their target proteins through multiple sites exhibit
much stronger binding strengths than their monovalent counterparts. In this work, we have …

Epidermal growth factor receptor (EGFR) is associated with the progression of a wide range
of cancers including breast, glioma, lung, and liver cancer. The observation that EGFR …

Continuous biosensors provide real-time information about biochemical processes
occurring in the environment of interest and are therefore highly desirable in research …