Inhibitors of glucosamine-6-phosphate synthase as potential antimicrobials or antidiabetics–synthesis and properties

J Stefaniak, MG Nowak, M Wojciechowski… - Journal of Enzyme …, 2022 - Taylor & Francis
Abstract Glucosamine-6-phosphate synthase (GlcN-6-P synthase) is known as a promising
target for antimicrobial agents and antidiabetics. Several compounds of natural or synthetic …

Efficient L-Proline catalyzed synthesis of some new (4-substituted-phenyl)-1, 5-dihydro-2H-pyrimido [4, 5-d][1, 3] thiazolo [3, 2a]-pyrimidine-2, 4 (3H)-diones bearing …

SH Sukanya, T Venkatesh, SJA Rao, MN Joy - Journal of Molecular …, 2022 - Elsevier
In the present study, a simple and efficient protocol has been developed to synthesize a
series of new (4-substituted-phenyl)-1, 5-dihydro-2H-pyrimido [4, 5-d][1, 3] thiazolo [3, 2a] …

Optoelectronic, DFT and current-voltage performance of new Schiff base 6-nitro-benzimidazole derivatives

K Upendranath, T Venkatesh, YA Nayaka… - Inorganic Chemistry …, 2022 - Elsevier
In the present work, we have synthesized a new Schiff base 6-nitro-benzimidazole derivative
(3a and 3b) and were confirmed by analytical and spectroscopic methods. TiO 2 …

Design, microwave assisted synthesis, and molecular modeling study of some new 1, 3, 4-thiadiazole derivatives as potent anticancer agents and potential VEGFR-2 …

SR Atta-Allah, AM AboulMagd, PS Farag - Bioorganic Chemistry, 2021 - Elsevier
A green and efficient method was developed for the synthesis of 1, 3, 4-thiadiazole based
compounds under microwave (MW) activation. The nucleophile N-(5-amino-1, 3, 4 …

One-pot synthesis of some new 7‑hydroxy-5-(4-substitutedphenyl)-9-methyl-1, 5-dihydro-2H-dipyrimido [1, 2-a: 4′, 5′-d] pyrimidine-2, 4 (3H)‑dione derivatives and …

K Upendranath, T Venkatesh, M Shashank… - Journal of Molecular …, 2022 - Elsevier
Metal-free organic dyes are gaining interest and demands in the field of light absorption and
light-emitting applications. In this study, we developed efficient one-pot synthesis of 7 …

[PDF][PDF] One-pot synthesis of novel substituted phenyl-1, 5-dihydro-2h-benzo [4, 5] thiazolo [3, 2-a] pyrimido [4, 5-d] pyrimidine derivatives as potent antimicrobial agents

T Venkatesh, YD Bodke, K Nagaraj, SR Kumar - Med Chem, 2018 - researchgate.net
In this paper, we have reported the synthesis of novel substituted phenyl-1, 5-dihydro-2H-
benzo [4, 5] thiazolo [3, 2-a] pyrimido [4, 5-d] pyrimidine derivatives (4a-m). The title …

Facile TiO2 NPs catalysed synthesis of substituted-4-Hydroxy/methoxy benzylidene derivatives as potent antioxidant and anti-tubercular agents

SH Sukanya, T Venkatesh, R Kumar… - Chemical Data Collections, 2021 - Elsevier
In this work, we report a facile synthesis of a series of substituted-4-hydroxy/methoxy
benzylidene derivatives (3a-i) via Knoevenagel condensation reaction of different active …

Facile synthesis of some 5-(3-substituted-thiophene)-pyrimidine derivatives and their pharmacological and computational studies

SH Sukanya, T Venkatesh, ASJ Rao… - Chimica Techno Acta …, 2021 - elar.urfu.ru
A series of 5-(3-substituted-thiophene)-pyrimidine derivatives (3a-d) were synthesized via
Knoevenagel condensation reaction in aqueous ethanol using H2O2: HCl as a catalyst …

Microwave-mediated approach to highly substituted nitropyrimidines via double Mannich reactions and their biological properties

C Gülbenek, M Yıldırım, A Yıldırım - Tetrahedron, 2022 - Elsevier
In the current study, new polysubstituted nitropyridimines were efficiently synthesized via
double Mannich cyclizations of diaryl substituted β-nitroenamines with formaldehyde and …

Three Step Synthesis of Fully and Differently Arylated Pyridines

M Arita, S Yokoyama, H Asahara… - European Journal of …, 2020 - Wiley Online Library
Condensation of β‐(2‐pyridyl) enamine and α, β‐unsaturated ketone in the presence of
FeCl3 under air afforded highly substituted pyridines. In this transformation, FeCl3 acted as …