Abstract Introduction The PReferentially expressed Antigen in MElanoma (PRAME) protein
has been shown to be an independent biomarker for increased risk of metastasis in Class 1 …

Uveal melanoma (UM), the most common primary intraocular cancer in adults, is among the
tumors with poorer prognosis. Recently, the role of the oncometabolite lactate has become …

Uveal melanoma (UM), a distinct subtype of melanoma, presents unique challenges in its
clinical management due to its complex molecular landscape and tendency for liver …

Background Class 2 uveal melanomas are associated with the inactivation of the BRCA1
((breast cancer type 1 susceptibility protein)-associated protein 1 (BAP1)) gene. Inactivation …

Simple Summary Our study looked at the usefulness of a protein called S100 in monitoring
the progression of uveal melanoma, a type of black skin cancer first growing in the eye. We …

Metastatic uveal melanoma continues to have a poor prognosis with distinct
pathophysiology from cutaneous melanoma and limited effective treatment options …

The vitreous is a vital component of the eye, occupying a substantial portion of its volume
and maintaining its structure. This study delves into the presence and significance of …

Melanoma is a form of skin cancer that develops in the skin's pigment cells, known as
melanocytes, and can spread via blood and the lymphatic system to nearby tissues or …

Objective Uveal melanoma (UM) poses significant diagnostic and prognostic challenges
due to its variable genetic landscape. We explore the use of a novel deep-learning tool to …

Purpose: The human cornea is essential for vision, providing structural integrity and
refractive power to the eye. Recent advancements have deepened our understanding of the …