Opioid Abuse in Chronic Pain — Misconceptions and Mitigation Strategies | New England Journal
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The prescribing of opioid analgesics for pain management—particularly for management of
chronic noncancer pain (CNCP)—has increased more than fourfold in the United States …

Objectives: Identify the etiology of opioid use disorder medical conditions and emergencies.
Outline the appropriate evaluation of opioid use disorder. Review the management options …

Background Long-term efficacy of opioids for non-cancer pain is unproven, but risks argue
for cautious prescribing. Few data suggest how long or how much opioid can be prescribed …

The prevalence of opioid use and misuse has provoked a staggering number of deaths over
the past two and a half decades. Much attention has focused on individual risks according to …

Importance With the current opioid crisis, it is important to improve understanding of the
biological mechanisms of opioid use disorder (OUD). Objectives To detect genetic risk …

BACKGROUND TO OPIOID USE DISORDER, TREATMENT PRINCIPLES, AND THE
ANESTHESIOLOGIST OUD is defined by the overpowering desire to obtain and use opioids …

The roots of the remarkably lethal US opioid crisis are complex and inextricably entangled
with healthcare, especially in its treatment of another serious health problem: pain. Failures …

The epidemic of opioid addiction is shaping up as the most serious clinical issues of current
times. Opioids have the greatest propensity to develop addiction after first exposure …

Importance Prior studies have found a substantial risk of persistent opioid use among
adolescents and young adults undergoing surgical and dental procedures. It is unknown …