Mechanistic insights into the immune pathophysiology of COVID-19; an in-depth review

A Shafqat, S Shafqat, SA Salameh, J Kashir… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which causes
coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In …

Role of specialized pro-resolving lipid mediators and their receptors in virus infection: a promising therapeutic strategy for SARS-CoV-2 cytokine storm

CH Lee - Archives of pharmacal research, 2021 - Springer
Unexpected viral infections outbreaks, significantly affect human health, leading to
increased mortality and life disruption. Among them is the severe acute respiratory …

COVID-19: Zinc and angiotensin-converting enzyme 2 (ACE2) deficiencies as determinants of risk and severity of disease: A narrative review

MP Salgo - Infectious diseases and therapy, 2021 - Springer
A growing body of evidence supports the premise that deficiencies of zinc and angiotensin-
converting enzyme 2 (ACE2, a zinc enzyme) determine severity of coronavirus disease 2019 …

[HTML][HTML] Toxicity of SARS-CoV-2 Spike Protein from the Virus and Produced from COVID-19 mRNA or Adenoviral DNA Vaccines

JF Lesgards, D Cerdan, C Perronne… - … of Microbiology & …, 2023 - fortuneonline.org
COVID-19 has already killed millions of people around the globe through severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection followed by immuno …

Predictors of mortality in COVID-19 patients treated with convalescent plasma therapy

N Rahimi-Levene, J Shapira, I Tzur, E Shiloah, V Peer… - Plos one, 2022 - journals.plos.org
Several options to treat hospitalized severe COVID-19 patients have been suggested. The
study aimed to describe survival in patients treated with convalescent COVID plasma (CCP) …

Aspectos gerais da COVID-19 e as possíveis consequências do uso indiscriminado de antimicrobianos durante a pandemia no Brasil

LOP Silva - 2023 - arca.fiocruz.br
Com milhões de casos e óbitos em todo o mundo, a COVID-19, causada pelo SARSCoV-2,
rapidamente se tornou uma emergência de saúde pública. Dada a gravidade e o número …

ADAM-17 Activity and Its Relation to ACE2: Implications for Severe COVID-19

J Sun, A Edsfeldt, J Svensson, T Ruge… - International Journal of …, 2024 - mdpi.com
There is a lack of studies aiming to assess cellular a disintegrin and metalloproteinase-17
(ADAM-17) activity in COVID-19 patients and the eventual associations with the shedding of …

Therapeutic Approaches in COVID‐19 Patients: The Role of the Renin‐Angiotensin System

F Ketabchi, S Jamzad - Canadian Respiratory Journal, 2022 - Wiley Online Library
Two and a half years after COVID‐19 was first reported in China, thousands of people are
still dying from the disease every day around the world. The condition is forcing physicians …

Acute Kidney Injury and Blood Purification Techniques in Severe COVID-19 Patients

M Napoli, M Provenzano, L Hu, C Bini… - Journal of Clinical …, 2022 - mdpi.com
Although most patients with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-
2) experience respiratory manifestations, multi-organ dysfunction is frequent. Almost 20% of …

Covid 19 May Limit the Use of Anti-hyperglycemic Agents. Does it Call for the Development of New Anti-hyperglycemic Agents?

N Sibiya, B Mbatha, C Arineitwe… - Current Diabetes …, 2022 - ingentaconnect.com
Diabetes mellitus has been identified as a major risk factor for developing severe COVID 19
complications. In this review article, the efforts were directed to provide insights and the …