Glycomimetics versus multivalent glycoconjugates for the design of high affinity lectin ligands

S Cecioni, A Imberty, S Vidal - Chemical reviews, 2015 - ACS Publications
One could certainly highlight a conceptual resemblance between social interactions as the
basis of societies and civilizations and the ability of molecules to interact in a noncovalent …

[HTML][HTML] Nanomaterial-based sensors for detection of foodborne bacterial pathogens and toxins as well as pork adulteration in meat products

BS Inbaraj, BH Chen - journal of food and drug analysis, 2016 - Elsevier
Food safety draws considerable attention in the modern pace of the world owing to rapid-
changing food recipes and food habits. Foodborne illnesses associated with pathogens …

Chemical strategies to target bacterial virulence

M Garland, S Loscher, M Bogyo - Chemical reviews, 2017 - ACS Publications
Antibiotic resistance is a significant emerging health threat. Exacerbating this problem is the
overprescription of antibiotics as well as a lack of development of new antibacterial agents …

High-Affinity Pentavalent Ligands of Escherichia coli Heat-Labile Enterotoxin by Modular Structure-Based Design

E Fan, Z Zhang, WE Minke, Z Hou… - Journal of the …, 2000 - ACS Publications
High-affinity protein ligands have wide applications in disease diagnosis, prevention, and
treatment. A promising strategy to arrive at such ligands is the creation of multivalent …

Glyconanoparticles for the colorimetric detection of cholera toxin

CL Schofield, RA Field, DA Russell - Analytical chemistry, 2007 - ACS Publications
Cholera continues to represent a major threat to human health, particularly in developing
countries. Death can be readily avoided when medical treatment is rapidly administered. In …

Recent trends in glycodendrimer syntheses and applications

YM Chabre, R Roy - Current topics in medicinal chemistry, 2008 - ingentaconnect.com
Carbohydrate protein interactions are at the front of several biological interactions spanning
from cell growth and differentiation, cell signaling, apoptosis, cancer, and microbial …

Multivalency in ligand design

VM Krishnamurthy, LA Estroff… - … -based approaches in …, 2006 - Wiley Online Library
We define multivalency to be the operation of multiple molecular recognition events of the
same kind occurring simultaneously between two entities (molecules, molecular aggregates …

Nanoparticle applications in food–a review

A Wasilewska, M Bielicka, U Klekotka… - Food & Function, 2023 - pubs.rsc.org
The use of nanotechnology in the food industry raises uncertainty in many respects. For
years, achievements of nanotechnology have been applied mainly in biomedicine and …

AB5 toxins: structures and inhibitor design

E Fan, EA Merritt, CLMJ Verlinde, WGJ Hol - Current opinion in structural …, 2000 - Elsevier
High-resolution crystal structures of AB5 toxins in their native form or in complex with a
variety of ligands have led to the structure-based design and discovery of inhibitors targeting …

Structural glycobiology: a game of snakes and ladders

ML DeMarco, RJ Woods - Glycobiology, 2008 - academic.oup.com
Oligo-and polysaccharides are infamous for being extremely flexible molecules, populating
a series of well-defined rotational isomeric states under physiological conditions …