Bioactivity and Pharmacological Potential of Date Palm (Phoenix dactylifera L.) Against Pandemic COVID-19: a Comprehensive Review
MR Ahmad Mohd Zain, Z Abdul Kari… - Applied biochemistry …, 2022 - Springer
A novel coronavirus disease (COVID-19) or severe acute respiratory syndrome-related
coronavirus 2 (SARS-CoV-2), transmitted from person to person, has quickly emerged as the …
coronavirus 2 (SARS-CoV-2), transmitted from person to person, has quickly emerged as the …
Rhamnetin, a nutraceutical flavonoid arrests cell cycle progression of human ovarian cancer (SKOV3) cells by inhibiting the histone deacetylase 2 protein
KK Bharadwaj, B Rabha, I Ahmad… - Journal of …, 2024 - Taylor & Francis
Overexpression of HDAC 2 promotes cell proliferation in ovarian cancer. HDAC 2 is involved
in chromatin remodeling, transcriptional repression, and the formation of condensed …
in chromatin remodeling, transcriptional repression, and the formation of condensed …
Macrolactin Metabolite Production by Bacillus sp. ZJ318 Isolated from Marine Sediment
L Zhang, M Jin, X Shi, L Jin, X Hou, Y Yu, B Liu… - Applied Biochemistry …, 2022 - Springer
A total of 172 microbial strains were screened and isolated from Arctic Ocean marine
sediments at a depth of 42~ 3,763 m. A microorganism with strong antibacterial activity …
sediments at a depth of 42~ 3,763 m. A microorganism with strong antibacterial activity …
Molecular modelling and structure-activity relationship of a natural derivative of o-hydroxybenzoate as a potent inhibitor of dual NSP3 and NSP12 of SARS-CoV-2: In …
The nsp3 macrodomain and nsp12 (RdRp) enzymes are strongly implicated in the virulent
regulation of the host immune response and viral replication of SARS-CoV-2, making them …
regulation of the host immune response and viral replication of SARS-CoV-2, making them …
Target specific inhibition of protein tyrosine kinase in conjunction with cancer and SARS-COV-2 by olive nutraceuticals
The fact that viruses cause human cancer dates back to the early 1980s. By reprogramming
cellular signaling pathways, viruses encoded protein that can regulate altered control of cell …
cellular signaling pathways, viruses encoded protein that can regulate altered control of cell …
Screening of phytocompounds for identification of prospective histone deacetylase 1 (HDAC1) inhibitor: an in silico molecular docking, molecular dynamics simulation …
The upregulation of HDAC1 facilitate the induction of epigenetic repression of genes
responsible for suppressing tumourigenesis, thereby triggering the development of cancer …
responsible for suppressing tumourigenesis, thereby triggering the development of cancer …
[HTML][HTML] Pharmacophore model-aided virtual screening combined with comparative molecular docking and molecular dynamics for identification of marine natural …
N Thangavel, M Albratty - Arabian Journal of Chemistry, 2022 - Elsevier
Abstract Targeting SARS-CoV-2 papain-like protease using inhibitors is a suitable approach
for inhibition of virus replication and dysregulation of host anti-viral immunity. Engaging all …
for inhibition of virus replication and dysregulation of host anti-viral immunity. Engaging all …
Multitargeted pharmacokinetics, molecular docking and network pharmacology-based identification of effective phytocompounds from Sauropus androgynus (L.) Merr …
E Gayathiri, P Prakash, M Ahamed… - Journal of …, 2024 - Taylor & Francis
According to worldwide health data, cancer, and inflammatory illnesses are on the rise and
are among the most common causes of death. Across the world, these types of health …
are among the most common causes of death. Across the world, these types of health …
In silico and in vitro evaluations of fluorophoric thiazolo-[2, 3-b] quinazolinones as anti-cancer agents targeting EGFR-TKD
Epidermal growth factor receptor tyrosine kinase domain (EGFR-TKD) plays a pivotal role in
cellular signaling, growth, and metabolism. The EGFR-TKD is highly expressed in cancer …
cellular signaling, growth, and metabolism. The EGFR-TKD is highly expressed in cancer …
High-efficiency breeding of Bacillus siamensis with hyper macrolactins production using physical mutagenesis and a high-throughput culture system
D Zhang, X Jiang, S Liu, M Bai, X Lin, Y Liu… - Journal of …, 2024 - Elsevier
Macrolactins have attracted considerable attention due to their value and application in
medicine and agriculture. However, poor yields severely hinder their broader application in …
medicine and agriculture. However, poor yields severely hinder their broader application in …