Metabolic reprogramming is reported to be one of the hallmarks of cancer, which is an
adaptive mechanism by which fast-growing cancer cells adapt to their increasing energy …

Metabolic reprogramming enables cancer cell growth, proliferation, and survival. This
reprogramming is driven by the combined actions of oncogenic alterations in cancer cells …

Background & Aims To identify gut and oral metagenomic signatures that accurately predict
pancreatic ductal carcinoma (PDAC) and to validate these signatures in independent …

Cancer treatment has been always considered one of the most critical and vital themes of
clinical issues. Many approaches have been developed, depending on the type and the …

Pancreatic ductal adenocarcinoma (PDA) is an aggressive malignancy typified by a highly
stromal and weakly immunogenic tumor microenvironment that promotes tumor evolution …

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy. PDAC is only
cured by surgical resection in its early stage, but there remains a relatively high possibility of …

This study explores the role of the long noncoding RNA (LncRNA) CRNDE in cisplatin
(CDDP) resistance of gastric cancer (GC) cells. Here, we show that LncRNA CRNDE is …

The tumorigenic mechanism for pancreatic ductal adenocarcinoma (PDAC) is not clear,
although chronic inflammation is implicated. Here, we identified an inflammatory cytokine …

Abnormal intracellular metabolism not only provides nutrition for tumor occurrence and
development, but also sensitizes the function of various immune cells in the immune …

Pancreatic cancer has one of the poorest prognoses of all malignancies, with little
improvement in clinical outcome over the past 40 years. Pancreatic ductal adenocarcinoma …