Small RNAs in bacteria and archaea: who they are, what they do, and how they do it

EGH Wagner, P Romby - Advances in genetics, 2015 - Elsevier
Small RNAs are ubiquitously present regulators in all kingdoms of life. Most bacterial and
archaeal small RNAs (sRNAs) act by antisense mechanisms on multiple target mRNAs …

sRNA-mediated control in bacteria: An increasing diversity of regulatory mechanisms

MG Jørgensen, JS Pettersen, BH Kallipolitis - Biochimica et Biophysica …, 2020 - Elsevier
Small regulatory RNAs (sRNAs) act as post-transcriptional regulators controlling bacterial
adaptation to environmental changes. Our current understanding of the mechanisms …

RNA-binding proteins involved in post-transcriptional regulation in bacteria

E Van Assche, S Van Puyvelde… - Frontiers in …, 2015 - frontiersin.org
Post-transcriptional regulation is a very important mechanism to control gene expression in
changing environments. In the past decade, a lot of interest has been directed toward the …

The previously uncharacterized RnpM (YlxR) protein modulates the activity of ribonuclease P in Bacillus subtilis in vitro

D Wicke, P Neumann, M Gößringer… - Nucleic Acids …, 2024 - academic.oup.com
Even though Bacillus subtilis is one of the most studied organisms, no function has been
identified for about 20% of its proteins. Among these unknown proteins are several RNA-and …

Regulation of mRNA stability during bacterial stress responses

DA Vargas-Blanco, SS Shell - Frontiers in microbiology, 2020 - frontiersin.org
Bacteria have a remarkable ability to sense environmental changes, swiftly regulating their
transcriptional and posttranscriptional machinery as a response. Under conditions that …

Understudied proteins and understudied functions in the model bacterium Bacillus subtilis—A major challenge in current research

D Wicke, J Meißner, R Warneke… - Molecular …, 2023 - Wiley Online Library
Abstract Model organisms such as the Gram‐positive bacterium Bacillus subtilis have been
studied intensively for decades. However, even for model organisms, no function has been …

An RNA-centric global view of Clostridioides difficile reveals broad activity of Hfq in a clinically important gram-positive bacterium

M Fuchs, V Lamm-Schmidt, J Sulzer… - Proceedings of the …, 2021 - National Acad Sciences
The gram-positive human pathogen Clostridioides difficile has emerged as the leading
cause of antibiotic-associated diarrhea. However, little is known about the bacterium's …

[HTML][HTML] Migration of surface-associated microbial communities in spaceflight habitats

D Marra, T Karapantsios, S Caserta, E Secchi… - Biofilm, 2023 - Elsevier
Astronauts are spending longer periods locked up in ships or stations for scientific and
exploration spatial missions. The International Space Station (ISS) has been inhabited …

A new role for CsrA: promotion of complex formation between an sRNA and its mRNA target in Bacillus subtilis

P Müller, M Gimpel, T Wildenhain, S Brantl - RNA biology, 2019 - Taylor & Francis
CsrA is a widely conserved, abundant small RNA binding protein that has been found in E.
coli and other Gram-negative bacteria where it is involved in the regulation of carbon …

Grad-seq identifies KhpB as a global RNA-binding protein in Clostridioides difficile that regulates toxin production

V Lamm-Schmidt, M Fuchs, J Sulzer, M Gerovac… - …, 2021 - academic.oup.com
Much of our current knowledge about cellular RNA–protein complexes in bacteria is derived
from analyses in gram-negative model organisms, with the discovery of RNA-binding …