Low exercise tolerance has a large influence on health status in chronic obstructive
pulmonary disease and chronic heart failure. In addition to primary organ dysfunction …

A vast amount of circumstantial evidence implicates oxygen-derived free radicals
(especially, superoxide and hydroxyl radical) and high-energy oxidants (such as …

Ischemia/reperfusion injury (IRI) is crucial in the pathology of major cardiovascular diseases,
such as stroke and myocardial infarction. Paradoxically, both the lack of oxygen during …

BACKGROUND: Curcumin has been shown to decrease ischemia-reperfusion (I/R) injury in
kidney or brain tissues. In this study, the effects of curcumin were evaluated in skeletal …

Peripheral artery disease (PAD) is caused by atherosclerosis in the lower extremities, which
leads to a spectrum of life-altering symptomatology, including claudication, ischemic rest …

Lipid peroxidation initiated by free radicals decreases the barrier function of cell membranes
and may be associated with muscle fiber necrosis and enzyme release following exercise [4 …

Background Dexmedetomidine (DEX) has been shown to decrease ischemia–reperfusion
(I/R) injury in kidney and brain tissues. In this study, the effects of DEX were evaluated in …

High altitude exposure leads to compromised physical performance with considerable
weight loss. The major stressor at high altitude is hypobaric hypoxia which leads to …

Objective: To investigate whether an inflammatory response occurs in patients undergoing
infrarenal aortic abdominal aneurysm repair, the localization and timing (ischemia and/or …

Oxygen-derived free radicals have been implicated in the pathogenesis of skeletal muscle
injury after ischemia–reperfusion. Caffeic acid phenethyl ester, an active component of …