To investigate whether the tumor suppressor gene PTEN affects the activity of the androgen
receptor (AR), we monitored the expression of the apoptotic gene HA-Bax (inserted in an …

The measurement of transcript levels constitutes the foundation of today's molecular
genetics. Independent of the techniques used, quantifications are generally normalised …

Although extracellular application of lysophosphatidic acid (LPA) has been extensively
documented to produce a variety of cellular responses through a family of specific G protein …

Ghrelin, a GH-releasing acylated peptide, has been recently identified from the rat stomach.
The purified peptide consists of 28 amino acids in which the serine 3 residue is n …

Although mechanisms for chromosomal instability in tumors have been described in animal
and in vitro models, little is known about these processes in man. To explore cytogenetic …

During pregnancy, the human extra-villous trophoblast in the contact zone between
maternal and fetal tissue in the placenta does not express the classical MHC class I and II …

Purpose: This study determined whether LL-37 (cathelicidin) is expressed by conjunctival
and corneal epithelia as part of ocular host defense. The antimicrobial activity of LL-37 was …

Using homology searches, we identified a novel human inhibitor of apoptosis (IAP) gene.
This gene has two splicing variants that contain open reading frames of 298 and 280 amino …

Collectins play important roles in the innate immune defense against microorganisms.
Recently, a new collectin, collectin 11 (CL-11 or CL-K1), was identified via database …

Microdissection of routinely stained or unstained frozen sections has been used successfully
to obtain purified cell populations for the analysis of cell-specific gene expression patterns in …