One hundred years of clostridial butanol fermentation

HG Moon, YS Jang, C Cho, J Lee… - FEMS microbiology …, 2016 - academic.oup.com
Butanol has been widely used as an important industrial solvent and feedstock for chemical
production. Also, its superior fuel properties compared with ethanol make butanol a good …

Chaotropicity: a key factor in product tolerance of biofuel-producing microorganisms

JA Cray, A Stevenson, P Ball, SB Bankar… - Current opinion in …, 2015 - Elsevier
Highlights•Disruption of cellular macromolecules by alcohols limits biofuel fermentations.•
Lignocellulose hydrolysis also generates chaotropic inhibitors (vanillin, phenolics …

Advances in developing metabolically engineered microbial platforms to produce fourth-generation biofuels and high-value biochemicals

MA Mehmood, A Shahid, S Malik, N Wang… - Bioresource …, 2021 - Elsevier
Producing bio-based chemicals is imperative to establish an eco-friendly circular
bioeconomy. However, the compromised titer of these biochemicals hampers their …

Pathway dissection, regulation, engineering and application: lessons learned from biobutanol production by solventogenic clostridia

S Li, L Huang, C Ke, Z Pang, L Liu - Biotechnology for biofuels, 2020 - Springer
The global energy crisis and limited supply of petroleum fuels have rekindled the interest in
utilizing a sustainable biomass to produce biofuel. Butanol, an advanced biofuel, is a …

[HTML][HTML] Reviving the Weizmann process for commercial n-butanol production

NPT Nguyen, C Raynaud, I Meynial-Salles… - Nature …, 2018 - nature.com
Developing a commercial process for the biological production of n-butanol is challenging
as it needs to combine high titer, yield, and productivities. Here we engineer Clostridium …

Energy-efficient butanol production by Clostridium acetobutylicum with histidine kinase knockouts to improve strain tolerance and process robustness

G Du, C Zhu, M Xu, L Wang, ST Yang, C Xue - Green Chemistry, 2021 - pubs.rsc.org
Under stress, Clostridium acetobutylicum sporulates and halts its metabolism, which limits its
use in industrial acetone–butanol–ethanol (ABE) fermentation. It is challenging to …

Cellulosic biobutanol by Clostridia: Challenges and improvements

MF Ibrahim, N Ramli, EK Bahrin, S Abd-Aziz - Renewable and Sustainable …, 2017 - Elsevier
The gradual shift of transportation fuels from oil based fuels to alternative fuel resources and
worldwide demand for energy has been the impetus for research to produce alcohol biofuels …

Engineering Clostridium for improved solvent production: recent progress and perspective

C Cheng, T Bao, ST Yang - Applied Microbiology and Biotechnology, 2019 - Springer
Clostridia are Gram-positive, spore-forming, obligate anaerobic bacteria that can produce
solvents such as acetone, ethanol, and butanol, which can be used as biofuels or building …

Production routes of advanced renewable C1 to C4 alcohols as biofuel components–a review

T Schubert - Biofuels, Bioproducts and Biorefining, 2020 - Wiley Online Library
In 2018, the EU's revised Renewable Energy Directive came into force, increasing
renewable energy targets for all energy sectors while limiting the use of first‐generation …

ATP regulation in bioproduction

KY Hara, A Kondo - Microbial cell factories, 2015 - Springer
Abstract Adenosine-5′-triphosphate (ATP) is consumed as a biological energy source by
many intracellular reactions. Thus, the intracellular ATP supply is required to maintain …