Artificial cells: past, present and future

W Jiang, Z Wu, Z Gao, M Wan, M Zhou, C Mao… - ACS nano, 2022 - ACS Publications
Artificial cells are constructed to imitate natural cells and allow researchers to explore
biological process and the origin of life. The construction methods for artificial cells, through …

Non-invasive delivery strategies for biologics

AC Anselmo, Y Gokarn, S Mitragotri - Nature Reviews Drug Discovery, 2019 - nature.com
Biologics now constitute a significant element of available medical treatments. Owing to their
clinical and commercial success, biologics are a rapidly growing class and have become a …

Inhibition of post-surgery tumour recurrence via a hydrogel releasing CAR-T cells and anti-PDL1-conjugated platelets

Q Hu, H Li, E Archibong, Q Chen, H Ruan… - Nature biomedical …, 2021 - nature.com
The immunosuppressive microenvironment of solid tumours reduces the antitumour activity
of chimeric antigen receptor T cells (CAR-T cells). Here, we show that the release—through …

[HTML][HTML] Future prospects for scaffolding methods and biomaterials in skin tissue engineering: a review

AA Chaudhari, K Vig, DR Baganizi, R Sahu… - International journal of …, 2016 - mdpi.com
Over centuries, the field of regenerative skin tissue engineering has had several
advancements to facilitate faster wound healing and thereby restoration of skin. Skin tissue …

Three-dimensional scaffolds for tissue engineering applications: role of porosity and pore size

QL Loh, C Choong - 2013 - liebertpub.com
Tissue engineering applications commonly encompass the use of three-dimensional (3D)
scaffolds to provide a suitable microenvironment for the incorporation of cells or growth …

The Poisson distribution and beyond: methods for microfluidic droplet production and single cell encapsulation

DJ Collins, A Neild, A DeMello, AQ Liu, Y Ai - Lab on a Chip, 2015 - pubs.rsc.org
There is a recognized and growing need for rapid and efficient cell assays, where the size of
microfluidic devices lend themselves to the manipulation of cellular populations down to the …

Deterministic encapsulation of single cells in thin tunable microgels for niche modelling and therapeutic delivery

AS Mao, JW Shin, S Utech, H Wang, O Uzun, W Li… - Nature materials, 2017 - nature.com
Existing techniques to encapsulate cells into microscale hydrogels generally yield high
polymer-to-cell ratios and lack control over the hydrogel's mechanical properties. Here, we …

Metre-long cell-laden microfibres exhibit tissue morphologies and functions

H Onoe, T Okitsu, A Itou, M Kato-Negishi, R Gojo… - Nature materials, 2013 - nature.com
Artificial reconstruction of fibre-shaped cellular constructs could greatly contribute to tissue
assembly in vitro. Here we show that, by using a microfluidic device with double-coaxial …

Applications of alginate microspheres in therapeutics delivery and cell culture: Past, present and future

D Dhamecha, R Movsas, U Sano, JU Menon - International journal of …, 2019 - Elsevier
Polymers are the backbone of pharmaceutical drug delivery. There are several polymers
with varying properties available today for use in different pharmaceutical applications …

[HTML][HTML] Artificial cells: from basic science to applications

C Xu, S Hu, X Chen - Materials Today, 2016 - Elsevier
Artificial cells have attracted much attention as substitutes for natural cells. There are many
different forms of artificial cells with many different definitions. They can be integral biological …