Neutrophil extracellular trap (NET) formation, first described in 2004 as a previously
unknown strategy of neutrophils to fight microbes, has attracted an increasing interest in the …

Beyond their well-known functions in the acute phases of the immune response, neutrophils
play important roles in the various phases of tumor initiation and progression, through the …

The risks of tumor recurrence following the successful resection of the primary tumor have
been known for decades; however, the precise mechanisms underlying treatment failures …

Patients with cancer have an increased risk of thromboembolism, which is the second
leading cause of death in these patients. Several mechanisms of the prothrombotic state in …

Neutrophils play a central role in innate immune defense. Advances in neutrophil biology
have brought to light the capacity of neutrophils to release their decondensed chromatin and …

Neutrophil extracellular traps (NETs) are webs of extracellular nuclear DNA extruded by
dying neutrophils infiltrating tissue. NETs constitute a defence mechanism to entrap and kill …

Cancer-associated thrombosis is a leading cause of non-cancer death in cancer patients
and is comprised of both arterial and venous thromboembolism (VTE). There are multiple …

Neutrophils are central mediators of innate and adaptive immunity and first responders to
tissue damage. Although vital to our health, their activation, function, and resolution are …

Thrombotic diseases seriously endanger human health, neutrophils and neutrophil
extracellular traps (NETs) play an important role in abnormal thrombus formation. NETs are …

L-Citrulline is a non-essential but still important amino acid that is released from enterocytes.
Because plasma levels are reduced in case of impaired intestinal function, it has become a …