Vascular endothelial growth factor (VEGF) is a pluripotent growth and permeability factor
that has a broad impact on endothelial cell function. The lung tissue is very rich in this …

COPD and asthma are important chronic inflammatory disorders with a high associated
morbidity. Much research has concentrated on the role of inflammatory cells, such as the …

Exaggerated levels of VEGF (vascular endothelial growth factor) are present in persons with
asthma, but the role (s) of VEGF in normal and asthmatic lungs has not been defined. We …

Airway and lung tissue remodeling and fibrosis play an important role in the development of
symptoms associated with lung function loss in asthma and chronic obstructive pulmonary …

Lipopolysaccharide (LPS) is involved in a variety of inflammatory disorders. Under stress
conditions, endoplasmic reticulum (ER) loses the homeostasis in its functions, which is …

Phosphatase and tensin homologue deleted on chromosome ten (PTEN) is part of a
complex signaling system that affects a variety of important cell functions. PTEN blocks the …

Introduction• The importance of angiogenesis in physiological and pathological conditions•
The contribution of immune cells to angiogenesis in inflammation and tumour growth• …

Recent data suggest that obstructive sleep apnea syndrome (OSAS) is an independent risk
factor for asthma exacerbations. Neuromechanical reflex bronchoconstriction …

Transcriptome-wide association studies (TWAS) are popular approaches to test for
association between imputed gene expression levels and traits of interest. Here, we propose …

Background There is increasing in vitro evidence to support a role for vascular endothelial
growth factor (VEGF), a major regulator of angiogenesis, as a mediator of fibrosis associated …